Professional Documents
Culture Documents
1997
HAMBRECHT & QUIST LLC
Growth
Pricing
Consolidation
New Technologies
Investment Strategies
In collaboration with
KNOWLEDGE ENTERPRISES, INC.
STOCK RECOMMENDATIONS
Stryker (Nasdaq/STRY - $30 1/8) — STRONG BUY
• EPS growth of 20% is intact and OP-1 is a potential kicker.
• Excellent risk/reward profile; 12-month target price $39.
DePuy (NYSE/DPU - $20 1/4) — BUY
• Industry leadership on sale; strong geographic and product diversity.
• Consistent share gainer and a proven consolidator with upside.
• Excellent risk/reward profile; 12-month target price $24.
Sofamor Danek (NYSE/SDG - $30 1/2) — BUY
• Spinal implant liability now quantifiable; key events to occur in January.
• Undervalued and the best takeover candidate long term.
• Relatively high-risk/high-reward profile; takeover value $60 minus liability.
Spine-Tech (Nasdaq/SPYN - $24 1/8) — BUY
• The hot play in fusion cages; the biggest near-term opportunity in orthopaedics.
• Positive 12- to 24-month outlook, but 1997 expectations look too aggressive.
• Fairly valued now; buy on dips or with outperformance.
Biomet (Nasdaq/BMET - ($15 1/8) — HOLD
• Low geographic and product diversity reduces growth potential.
• Moderate size impedes growth through acquisition.
• Without acquisitions, EPS risk is likely on the downside.
OrthoLogic (Nasdaq/OLGC - $5 3/4) — HOLD
• Transition to direct sales for bone growth stimulators put brakes on growth.
• Regrouping may require one or two more quarters; wait for bottom.
Product is the best, and long-term outlook is good.
Table of Contents
Investment Theme. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Out of Adversity Comes Opportunity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Waiting for Consolidation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
Potential Risks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
A Brief History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
Industry Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
The Reconstructive Device Market . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
Long-Term Developments: Goals and Technologies to Watch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Mix Shift and Pricing in the U.S. Market . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Pricing Forecast: Partly Sunny. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Winning in the Future: To Contract or Not to Contract?. . . Contract!. . . . . . . . . . . . . . . . . . . . . . . 14
The Ex-United States Reconstructive Device Market . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
The Players . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
The Trauma Market . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
Long-term Developments: Goals and Technologies to Watch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
The Spinal Implant Market . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
Long-term Developments: Goals and Technologies to Watch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
Lumbar Spinal Implant Market Outlook Discussion. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
Fusion Cages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
The U.S. Lumbar Instrumentation Market. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
The Players . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
Osteobiologics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
Soft Tissue Repair/Sports Medicine Market . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
Arthroscopy/Sports Medicine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
Bone Substitutes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
Company Profiles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Stryker Corp. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
DePuy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
Biomet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
Appendix . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
List of Exhibits
INVESTMENT THEME
Potential Risks
We feel that most risks are at least adequately discounted. A key risk for the
orthopaedic industry could be the impact of potential Medicare reform in 1997. It
appears clear that the Republican Congress has little enthusiasm for grabbing this hot
potato, but there are likely to be some cuts to "reduce the rate of growth." The
A BRIEF HISTORY
History is important For those new to the metal-bending industry of healthcare, a brief chronicle of the
because it is being orthopaedic industry may give context to our analysis and predictions. The history is
undone. important because much of it is being undone or rewritten with current trends.
Just 30 years ago, the industry was in its proverbial swaddling clothes. Previously,
joints were fused and functionality was not reestablished. The predominant therapy was
painkillers and a cane. Replacements for the hip came first, followed closely by the knee.
The roster of industry players grew largely through the defection of disgruntled
engineers and sales managers from successive generations of companies.
The benefit of the new hips and knees was enormous, relieving pain and restoring
function with low risk. As procedures grew from just a few hundred thousand in the mid-
1980s to almost 1,000,000 for hips and knees worldwide today, the companies
introduced more and more features and benefits. Porous coatings were used to enhance
bone ingrowth and reduce side effects from cement. The cost-plus environment allowed
prices to escalate 10% to 20% per year.
Three factors conspired to put the brakes on growth. First, the introduction of DRGs
by Medicare in the 1980s turned implants from profit generators in a cost-plus system
into costs in a flat-procedure-fee system. Hip replacements were targeted for especially
low reimbursement rates. This was the first domino in a chain effect leading to large
buying groups and the cost pressures experienced by hospitals today. The knee and hip
businesses were especially hard hit because volumes were big, exposure to Medicare
was large (90%), and the implant itself made up a large proportion of the procedure cost.
Medicare has kept increases in reimbursement well below inflation for several years, as
well, and many hospitals still lose money on the procedure.
Second, procedure growth slowed as nearly full penetration was reached at about
70% of all eligible patients. Third, and most important today, the much-touted high
technology premium products proved to be of little clinical value for less active patients
relative to the cemented products. The financial result of this trend has been steadily
declining share for high-priced units, and an overall decline in average selling prices
(ASPs) due to the mix shift. We believe this trend is largely over, contributing to our
comfort with investment in the industry.
With the rise of contract buyers in the United States, territory representatives
became less important, and with declining ASPs, distributor profits were crushed, often
decreasing the quality of coverage. At present, the core industry is restructuring in a shift
from independent to direct sales people. The shift allows companies to control the
customer contact and capture distributor margins, and, in some cases, ensure adequate
sales coverage. This shift is perhaps 65% complete, and some companies may never
shift to direct forces.
Cost reduction has kept pace with price reductions thus far. Manufacturing is a job
shop process. Costs are reduced with better processes and work flow and elimination of
non clinical-value-added elements, such as high-polish finishes and less expensive
INDUSTRY OVERVIEW
This overview covers key industry segments and statistics and places particular Key issues include
focus on issues and segments relevant to growth and investment value. The key issues pricing in
highlighted include pricing in reconstructive devices, with new analysis showing the reconstructive devices,
dominant and diminishing impact of product mix on this trend, indicating a near-term and the trend toward
uptick in growth. Quantification of the trends driving pure pricing declines points to contracts.
moderating, but continuing minor price pressure. Discussion of the trend toward
contracts in the reconstructive segment highlights existing market share as the key
competitive advantage. The key segments highlighted are reconstructive devices, spinal
implants, and osteobiologics, while others are covered in less detail.
The orthopaedic products market generated estimated worldwide sales of
$7.2 billion in 1995. It is characterized by a high degree of fragmentation and consists
of both high growth and low growth segments. By far, the largest segment of the
orthopaedic products market is reconstructive devices, mainly hip and knee prostheses,
with estimated worldwide sales of $3.6 billion in 1995, nearly 50% of the market. The
reconstructive device market is mature in the developed world, with approximately 6%
unit growth and 3% dollar growth in the United States in 1995, and 3% unit growth and
4% dollar growth ex-United States, for worldwide dollar growth of 3.3%.
Exhibit 1
U.S. Market
Procedures 3.2% 5.4% 6.4% 5.3% 5.1% 5.2% 5.2% 5.2%
Mix (2.9) (2.6) (2.1) (2.1) (1.1) (0.6) (0.4) 0
Price 2.0 (0.1) (1.7) (1.9) (2.4) (2.0) (1.8) (1.3)
Total 2.3 2.7 2.6 1.4 1.6 2.5 3.0 3.9
Ex-U.S. Market 6.0 5.0 4.0 4.0 3.0 4.0 5.0 5.0
Worldwide 4.2% 3.9% 3.3% 2.7% 2.3% 3.3% 4.0% 4.4%
In a quest for growth, many major orthopaedic companies are diversifying into high In a quest for growth,
growth segments of the orthopaedic market such as trauma, spinal implants, many companies are
osteobiologics, and sports medicine. This diversification has leveraged the larger diversifying into high
companies’ market power into the smaller markets, resulting in significant consolidation growth segments.
of the industry as a whole.
Other
10%
Spine
6%
Soft Goods
10% Reconstructive
Devices
50%
Arthroscopy/SM
10%
Trauma
14%
Exhibit 3
Market Growth
US Reconstructive Market Growth - Hips
1992 1993 1994 1995 1996 1997 1998 1999 2000
Procedures 2.6% (1.3%) 4.5% 4.5% 4.5% 4.0% 4.0% 4.0% 4.0%
Mix Impact (3.4%) (3.2%) (3.0%) (3.3%) (2.0%) (1.5%) (1.0%) 0.0%
Price 3.9% (0.8%) (1.4%) (2.5%) (3.0%) (3.0%) (2.0%) (1.5%) (1.0%)
Total Growth (5.5%) (0.1%) (1.0%) (1.8%) (1.0%) 0.5% 1.5% 3.0%
Reconstructive Market
1992 1993 1994 1995 1996 1997 1998 1999 2000
Procedures 3.5% 3.2% 5.4% 6.4% 5.3% 5.1% 5.2% 5.2% 5.2%
Mix Impact 0.0% (2.9%) (2.6%) (2.1%) (2.1%) (1.1%) (0.6%) (0.4%) 0.0%
Price 5.5% 2.0% (0.1%) (1.7%) (1.9%) (2.4%) (2.0%) (1.8%) (1.3%)
Total Growth 0.0% 2.3% 2.7% 2.6% 1.4% 1.6% 2.5% 3.0% 3.9%
Ex-US Market 6.0% 5.0% 4.0% 4.0% 3.0% 4.0% 5.0% 5.0%
Worldwide Growth 4.2% 3.9% 3.3% 2.7% 2.3% 3.3% 4.0% 4.4%
Growth in the core geographic markets — the United States, Western Europe, and
Japan — is expected to come mainly from the growing populations of elderly persons,
and greater demand resulting from an increasingly fitness-oriented population,
reduction in procedure risks, improvement in implant technology, increased use of
implants in younger patients, and development of orthopaedic procedures for other body
parts. In the emerging markets, particularly Asia, growth should come from greater
demand resulting from increasing economic prosperity, an aging population, and low
current penetration rates for orthopaedic implant procedures.
Background
A hip or knee replacement is clinically indicated for a patient with osteoarthritis,
rheumatoid arthritis, aseptic necrosis, or fracture leading to severe joint pain and/or
limited range of joint motion. It can be categorized as either primary or revision. A
revision replacement is clinically indicated when infection of the joint occurs or when
50.0%
45.0%
40.0%
35.0%
30.0%
Hips
25.0%
Knees
20.0%
15.0%
10.0%
5.0%
0.0%
Q1 93
Q2 93
Q3 93
Q4 93
Q1 94
Q2 94
Q3 94
Q4 94
Q1 95
Q2 95
Q3 95
Q4 95
Q1 96
Q2 96
Q3 96
Source: IMS America; H&Q estimates
Two factors converged to drive this mix shift. First, clinical data were generated
showing little benefit to porous implants for less active patients. Specifically, outcomes
for older and less active patients were as good with cemented hips. The second factor
was the meager annual increases of 0% to 2% in reimbursement under the Medicare
DRG code 209, which covers over 90% of hip and knee procedures. Until 1995, hip
procedures lost money for the average hospital, bringing significant pressure on implant
suppliers. Implants had risen to near 30% of costs of a total hip procedure by 1995 as
other costs were reduced.
With the rise of cost pressures, a new phenomenon arose, known as “patient demand
matching.” With patient demand matching, orthopaedic surgeons choose porous coated
implants for younger, more active patients with longer life spans and greater need for
mobility, and cemented implants for elderly or less active patients who are likely to be
outlived by their implants. The consequence has been the shift away from use of porous
coated implants since 1993.
Clearly, there is a place for porous coated implants in the reconstructive device
market and, in fact, it appears that the shift from porous coated to cemented implants has
largely run its course, as porous coated implants appear to have reached their clinically
justified level of usage. Moreover, some porous coated implant manufacturers
(particularly Biomet) have demonstrated that the fully costed economics of porous coated
and cemented implants are comparable. This calculation includes the additional
procedure time (15 to 20 minutes) and the cost of the cement and cement-related
accessories. Biomet has largely avoided the mix shift hit to sales as a result of this strategy.
Industry
Hips -3.2% -3.0% -2.2%
Knees -2.0% -1.4% -1.2%
Zimmer
Hips -3.9% -0.5% -3.3%
Knees -0.9% -1.0% -0.5%
DePuy
Hips -3.5% -5.9% -5.4%
Knees -5.1% -3.2% 2.7%
Howmedica
Hips -4.2% -7.5% -6.2%
Knees -2.8% -2.7% -2.7%
Biomet
Hips -2.7% -1.6% 2.0%
Knees -1.6% -0.3% -1.2%
We estimate that the shift from porous coated to cemented implants negatively
impacted U.S. knee implant revenue from -1% to -2% per year and U.S. hip implant
revenue around -3% per year from 1994 to 1996 Stabilization of this trend definitively
brightens the outlook for the reconstructive device market.
*Captures costs for: routine/special care nursing, operating room, laboratory, radiology, pharmacy, medical
supplies and other ancillary services
Source: CHIPS, company price lists
The Players
The reconstructive device market is highly fragmented and intensely competitive.
The major players include DePuy, Biomet, Osteonics, a division of Stryker, Zimmer, a
subsidiary of Bristol-Myers Squibb, Howmedica, a subsidiary of Pfizer, Smith &
Nephew, Johnson & Johnson Professional Inc., a division of Johnson & Johnson, and
Intermedics, a division of Sulzer Orthopaedics. Market shares are clustered very tightly,
with DePuy and Zimmer neck and neck with about 22% to 23% share in the hip implant
market, and Zimmer leading the knee implant market with about 22% share, with several
other manufacturers posting double digit market shares.
45%
40%
35%
30% Biomet
DePuy
25% Howmedica
Osteonics
20%
Richards
Zimmer
15%
10%
5%
0%
1990 1991 1992 1993 1994 1995
30%
25%
Biomet
20% Depuy
Howmedica
Intermedics
15%
J&J
Osteonics
10% Richards
Wright
Zimmer
5%
0%
1990 1991 1992 1993 1994 1995
Exhibit 9
Europe
Europe24%
24%
U.S.
U.S
56%
56%
Asia/Other
Asia/Other
20%20%
In the United States, cervical (upper spine) fusions appear to be growing at over
10%, and penetration of implants is rising rapidly. The cervical market is primarily a
U.S. business, with $45 million in the United States and $65 million worldwide. Growth
has been driven by the increase in cervical fusions due to increasingly good results with
the procedure, and through penetration of implants into the procedures. Synthes has
dominated this business in the United States, but Sofamor Danek has made substantial
inroads. Growth in this segment likely has a couple more years before the procedures are
fully penetrated.
Lumbar fusions appear to be almost flat, at 78,000 in 1995, and the rate of implant We expect growth in
usage is rising slightly. The lack of growth is driven by payers who object increasingly lumbar procedures to
to the poorly proven benefit of fusion surgeries. Overall, procedure growth appears to be increase to 10% with
around 4% in the United States. We expect growth in lumbar procedures to increase to the introduction of
10% with the introduction of fusion cages due to the well-documented benefits of the fusion cages.
product. We expect procedures to grow at 7% in Europe, with remaining growth coming
from increased penetration of implants into procedures performed. We include complete
projections and segmentation of the lumbar spinal implant market in the Appendix.
Background
There are three primary surgical procedures on the spine: laminectomy, discectomy,
and fusion. Laminectomy is a decompression procedure in which part of the spine is
removed to relieve pressure on the surrounding nerves. A discectomy is the removal of
all or a portion of a herniated disc. Neither discectomy nor laminectomy generally
involves device implantation.
Spinal fusions are performed to eliminate the pain caused by a number of factors.
The three primary ones are: pain due to degeneration of disks between vertebrae and the
occasional associated malalignment (70% of patients); trauma, including auto accidents
and removal of tumors (20% combined); and spinal deformities such as scoliosis, the
severe lateral curvature of the spine (10%). In trauma and degenerative disc disease, pain
and reduced function occur as the deformation of the spine causes contact between the
bony spine and the nerves emanating from the spinal column. The common fusion
procedures are: fusion with bone graft without instrumentation, and fusion with bone
graft with plates, screws, hooks, or rods.
The spinal fusion market has anatomic and severity segments which drive product
selection. The spine has three sections: upper, or cervical spine, the middle, or thoracic
spine, and the lower, or lumbar spine.
Cervical fusions have Cervical fusions have been the fastest growing segment as surgeons increase their
been the fastest growing usage of implants. Upper vertebrae bear less load and are much smaller than the lower
segment. vertebrae, requiring minimal support. Until recently, instrumentation was not often used
in cervical fusions. The implants used are simple plates and screws similar to trauma
products. In Europe, fusion cages are available for cervical procedures but are in early-
stage development in the United States (Spine-Tech). Although constituting almost half
of spinal fusion procedures, cervical fusions generate on the order of $500 per
instrumented procedure versus $2,000 for lumbar procedures. Almost all surgeries for
deformities or trauma are instrumented with hooks, rods, screws, or plates.
80% Cervical
47%
47%
70%
32%
60%
Cerv
50% Thoracic
16% Thor
16%
40% Lum
30%
50%
20% Lumbar
38%
38%
10%
0%
Procedures Dollars
The interbody fusion cage (fusion cage, or cage, shown in Exhibit 11 on the
following page) is the most exciting "new" technology for spinal surgeons, particularly
in view of the potential for laparoscopic implantation. Fusion cages have been marketed
in Europe for years to a modest reception. Fusion cages are generally cylindrical, around
0.5 inches in diameter, hollow, and with holes in the sides (like rolled swiss cheese). Two
fusion cages are inserted in the disc space side by side, protruding into the top and
bottom vertebrae, and filled with bone fragments harvested from the patient to enhance
possibility of fusion. The fusion cages reestablish disc height, and thereby restore the
proper anatomy (likely relieving pressure on nerves), and bone grows through the holes
and around the fusion cages for a fusion. They provide proper physiological support,
through the vertebral bodies of the spine. Threads on the exterior of the cage prevent the
cage from slipping out of the hole into which it was implanted or protruding through the
other side. The devices can be implanted in an open procedure or with laparoscopic
techniques.
The FDA approved two fusion cages, Spine-Tech’s BAK/L and U.S. Surgical’s Ray
Threaded Fusion Cage, in the fall of 1996. Fusion cages are entering a highly receptive
market. In a quirk of fate, fusion cages are the first products approved by the FDA for
general lumbar fusion. Pedicle screw and plate constructs, the present standard of care,
have not been approved for this use
Severity segments are based on the number of levels to be fusioned, the degree of
stabilization required, and the activity level of the patient. Where disc degeneration or
trauma afflicts multiple levels of the spine, implants are almost always used. Older or
less active patients are less likely to receive an implant.
L4 L4
Healthy L4
Disc
L5 L5
L5
S1
Diseased
Disc
Pre-Operation Post-Operation
Source: Spine-Tech
In the United States, we estimate implant usage in around 77% of total lumbar
fusion procedures. An estimated 60% of fusions of a single level of the lumbar spine
used an implant in 1995. We believe that fusion cages will increase the rate of implant
usage. Instrumentation would undoubtedly be above the present penetration level in the
United States were it not for the pedicle screw lawsuits, catalyzed by a December 17,
1993, "20/20" episode highlighting the off-label usage of pedicle screws and supposed
harm done to patients. Since then, the growth of lumbar fusion procedures has not fully
recovered, with negative growth rates for 1993/94 and 1994/95. Most spinal implant
companies selling pedicle screws have now been granted approval for limited
applications in the lumbar spine. A process is underway to downclassify pedicle screw
constructs from Class III (requiring clinical trials) to Class II (510 (k)). This process is
moving at a glacial pace.
Fusion Cages
We believe that fusion cages are likely to push U.S. growth in the lumbar spine
market, 50% of the total, to near 20% over the next few years, with traditional pedicle
screw products flat or declining in growth. Fusion cages appear to have almost every
factor in their favor for rapid and deep penetration into the spinal market. The primary
reasons why fusion cages should reach their potential are:
Exhibit 12
Modality
Standard Non-Instrumented
Fusion Cage Instrumentation Procedure
* Kuslich: Average ** Zdeblick; small study, *** estimated 1 level from # Yuan, et al, excluding
## Industry/NCHS significant Yuan, et al stimulators
Other benefits are likely to include reduced blood loss and reduced operating time
of 60 to 90 minutes against several hours for present procedures, which increases a
surgeon’s output and income. Fusion cages are likely to save money in the procedure
alone. Our estimates show up to $3,600 savings for a single-level fusion compared to a
non-instrumented procedure, or $2,300 compared to an instrumented procedure.
Savings are less in multi-level procedures. Further savings are likely to accrue to
workers compensation insurers through the faster recovery and return to work.
OSTEOBIOLOGICS
All procedures and devices under discussion to this point have focused on
mechanical reconstruction or repair of bone and cartilage. Autograft, plates, screws,
spinal fusions, and coatings on hip and knee replacements seek to harness and facilitate
bone’s regenerative properties. Osteobiologics represent products delivered locally to
actively and passively stimulate and accelerate bone’s regenerative properties. Such
products have long been imagined and held out as the next revolution in orthopaedics.
Products become imaginable for everything from injectable fixation of fractures, to
superior bonding for hip implants, to reducing reoperation rates for hard-to-repair
fractures, to injectable or minimally invasive spinal fusion products, to replenishment of
bone lost to revision arthroplasties, osteoporosis, or tumors. The ultimate market
potential is large, will be slow in coming, and well worth the effort. Perhaps the major
challenge in the development of osteobiologics has been and will continue to be the
carrier, the material which controls the release of the agents to the site of treatment.
Exhibit 13
Non/Delayed-Union Fractures
Number of Procedures 50,000
Cost per Patient $3,000
Market Potential Value $150,000
Arthroscopy/Sports Medicine
Arthroscopy is closely aligned with endoscopy, involving minimally invasive
instruments and visualization technologies for diagnosis and surgery on joints. While
many of the same companies compete, the market shares are different because
arthroscopists are a different and smaller call point, the sports medicine or knee
BONE SUBSTITUTES
Most bone substitutes seek to provide a matrix through which natural bone can
regrow. Current bone substitutes, referred to as osteoconductive agents, have
disadvantages preventing widespread adoption by physicians. They lack the structural
integrity and strength of natural bone, and migration from the site of application and
degradation over time are difficult to control. As a result, their use has been limited to
non-weight bearing clinical indications, such as treatment of wrist fractures. As more
advanced osteoconductive agents are developed, we believe the market has the potential
to expand dramatically.
The U.S. market for osteoconductive agents had 1995 estimated sales of about
$21 million, with estimated ex-U.S. sales of $104 million. We believe that the market is
in its infancy and has great long-term growth potential, as new technologically advanced
products with new indications reach the marketplace.
Currently, autograft (patient’s own bone) is considered the gold standard in
procedures requiring supplemental bone. However, the harvesting of autograft, usually
from the patient’s pelvis (iliac crest), can be painful, and this second procedure increases
the risk of infection. When autograft is not available or can not be easily obtained,
allograft bone (bone sourced from a cadaver) is an alternative. Obtained primarily from
bone and tissue banks and secondarily from companies (e.g., Osteotech, Cryolife,
Biodynamics International), allograft eliminates pain associated with the harvesting of
autograft bone, but its strength may be compromised by sterilization techniques. In
addition, infectious diseases may be transmitted from allograft donor bone, although the
risk is minimal at best, with Osteotech reporting no confirmed incidents with over
750,000 allograft units of transplant tissues. Allograft products currently available from
Osteotech include its demineralized bone matrix (DBM), in a flexible configuration that
is easily moldable and, more recently, in putty-like forms.
Another alternative to autograft is synthetic bone graft, most of which is made up of
collagen, hydroxylapatite (HA), tricalcium phosphate, or some combination of these
materials. Interpore, Zimmer (developed with Collagen Corporation), Wright Medical
Technology, and Orthofix all have FDA-approved bone graft substitutes for orthopaedic
and craniofacial applications.
FY Dec. 1995A 1996E 1997E Endoscopic Equipment Cash per Share $2.58
Stretchers and Beds Total Debt $97 mil.
FY EPS $0.90 $1.08 $1.29
Powered Surgical Instruments
FY Rev. (mil.) $872.0 $912.6 $1,021.4
FY Rev. Growth 27.9% 4.7% 11.9% Dow Jones 30 6560.91
Net Income/Loss Nasdaq Composite 1291.38
24
• 12-month target price is $39.
22
20
Millions
3.84
1.92
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov
OVERVIEW
Stryker’s core businesses include reconstructive devices, including hip, knee
trauma, spinal implants, trauma, endoscopic equipment, powered surgical instruments,
stretchers and beds, and physical therapy services. When Stryker reports its operating
results, the company includes sales of reconstructive devices, spinal implants,
endoscopic equipment; powered surgical instruments in its Surgical Products Category;
and sales of patient care and handling products and physical therapy services in its
Medical Products Category. Additionally, since acquiring a majority interest in its
Japanese distributor, Matsumoto-Medical Instruments, Inc., Stryker has reported sales
of Matsumoto distributed products, representing products sourced by Matsumoto from
other companies for sale in Japan.
Exhibit 14
Many of us have shaken our head in a mixture of awe and disbelief during investor
presentations where John Brown presents his final slide, “20%,” which features a big
smiley face. After 20 years of 20% growth in earnings per share, it is mostly awe. It is
an eventuality that investors now take for granted, and has allowed the stock to trade at
a multiple premium and appreciate dramatically. The question on the minds of Stryker
watchers is whether Stryker’s business endeavors can support 20% in earnings per share
growth in the near and medium terms. For those of us investigating the Stryker story for
the first time, we want to be sure this is not the first quarter or year the company misses
the golden mark.
Exhibit 15
FY 1994 FY 1995
One goal that is oddly lacking in the Stryker ethos is a stated desire for leadership
in the markets in which it competes. Of course, by being “better” and gaining share, the
end result should be leadership. However, we would not expect the company to make a
dramatic move, such as a large acquisition, to achieve it in the short term. In the United
States, the company is number two in Powered Instruments, number three in
arthroscopy, number two in endoscopy, and number five in reconstructive orthopaedics
(hips/knee units). It is number two in reconstructive implants in Japan, and a smaller
player in Europe.
In summary, we believe that Stryker has a firm a grip on its business and growth. We believe that Stryker
This view is based on an assessment of the reported numbers, which are exceedingly has a firm a grip on its
clear in showing ongoing growth, and of the underlying business segments in which the business and growth.
company competes. If there is a point with which we agree broadly with the skeptics, it
is that Stryker’s underlying businesses are not growing as much as they once did,
especially from a U.S.-only perspective. Arthroscopy, endoscopy, and reconstruction all
drove dramatic growth at one time in the United States. We are not claiming dramatic
growth as a goal for Stryker, however, at 20% for earnings per share, and we do not
expect dramatic outperformance. In the near term, Stryker is likely to derive growth
above and beyond its markets from geographic expansion, new products in existing
segments, and continued entry into new segments, including trauma and spinal implants.
All things considered, we believe that Stryker should be able to meet our target with
relative ease.
PRODUCT SEGMENTS
GEOGRAPHIC SEGMENTS
As Stryker evolves into the major player it is becoming, expanding geographic Expanding geographic
coverage becomes an effective source of growth and profitability. Like most major coverage is an effective
medical device companies, Stryker’s primary market is the United States, comprising source of growth and
55% of sales. It is also the most consistent performer. In the United States, the product profitability.
divisions are independent. Europe is relatively small, at under 14% of sales in 1995, but
is showing excellent growth. We expect Europe, growing around 20% on the top line
without acquisitions, to be a major focus for Stryker for internal and acquired growth in
the near term.
The U.S. market for most of Stryker’s products is enjoying a recovery bounce since The U.S. business has
the “Hillary” scare of 1994. The base business, combined with new products and a minor an underlying growth
lift from the acquisition of distributors gives the U.S. business an underlying growth rate rate of 20% so far in
of 20% so far in 1996, including some negative impact from mix shift in the Osteonics 1996.
division. In the short term, it appears that the stretcher and bed division will be the star
performer and contributor to profit growth. Stryker sells most of its products in the
United States through a direct sales force of about 340 representatives. The company
maintains a separate and dedicated sales force for each of its main product lines.
Uniquely, most of the Surgical division sales people are compensated on straight
commission, with no upper limit. This fact emphasizes how strongly Stryker feels about
hiring the best sales people. Reconstructive devices are sold through a combination of
direct sales representatives (or commissioned agents) and independent stocking
FY Dec. 1995A 1996E 1997E Spinal Implants Cash per Share $2.03
Trauma Devices Total Debt $46 mil.
FY EPS $1.05 $1.17 $1.21
Sports Medicine Products
FY Rev. mil. $636.5 $698.3 $764.5
Operating Room Supplies
FY Rev. Growth 15.3% 9.7% 9.5% Dow Jones 30 6560.91
Net Income/Loss Nasdaq Composite 1291.38
Millions
5.55
2.78
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov
INVESTMENT OVERVIEW
When the going gets tough, the tough get going. DePuy is the tough guy in
orthopaedics that can gain share and leadership in its core business and leverage its
strengths into higher-growth segments. In an increasingly competitive industry with
several medium-sized players, we look for a heavyweight player like DePuy to
capitalize on the change, and DePuy already has a track record of doing so. DePuy is the
number-three player in orthopaedics, and the only major player gaining share. Besides
its core reconstructive business, the company plays in reconstructive devices, spinal
implants, trauma, sports medicine, and soft goods/operating room supplies.
The woes of the core hip and knee businesses in the orthopaedic industry are well
documented, and likely exaggerated (see attached industry overview). We believe that
DePuy’s large exposure to these businesses may lead some to avoid the investment, even
at 14.75 times 1997 in EPS. Investment in DePuy is investment in long-term industry
leadership, at a valuation that does not reflect its long-term potential.
In summary, then, we recommend DePuy stock as a long-term holding that should
offer 15% annualized returns with relatively low risk and upside potential. At 16.75
times our 1997 estimate of $1.21 in EPS with 15% earnings growth going forward, the
stock does not carry a premium to the S&P 500, although we feel it should because of
market leadership, low risk attached to projected growth, and high probability of
outperformance. Our 12-month target price is $24, based on 17 times our 1998 estimate
of $1.38 in EPS.
GROWTH DRIVERS
• DePuy’s leadership (number two in the United States and number three worldwide)
in the reconstructive device market should provide competitive advantage in
winning contracts and market share.
• DePuy’s global distribution network should drive continued strong growth outside
the United States and power the introduction of internally developed or acquired
product lines.
• DePuy’s stated acquisition-oriented growth strategy should allow the company to
achieve further geographic and product diversification.
• Management’s solid history of execution fosters confidence in its ability to grow the
business beyond the core reconstructive device franchise.
• We look for top-line growth of 10%, with 9% from base business growth and 1%
from acquisition. Operating leverage and cost reductions bring EPS growth to 12%
as the company leverages its new direct sales forces.
We anticipate that sales growth in DePuy’s base businesses, which now include
reconstructive devices, spinal implants, trauma, and soft goods/operating room supplies
should be around 9% to 10% going forward for two years. The acquisition of Orthopedic
Technology, in March 1996, should add another 3% to 5% to total growth through the
first quarter of 1997. Additional sales growth should come from future acquisitions. We
would expect bottom-line growth to exceed top-line growth as DePuy continues to
reduce costs and leverage its new direct distribution force. Our projections assume no
further acquisition, leaving upside potential.
Exhibit 18
Reconstructive Devices
DePuy is the leading manufacturer of hip implants in the United States and number-
three worldwide, with market shares of 22% and 16%, respectively, representing U.S.
sales of $152 million and worldwide sales of $268 million. The company is number-four
in knee implants in the United States and worldwide, with market shares of 13%,
representing U.S. sales of $100 million and worldwide sales of $182 million,
respectively. In the extremities (mainly shoulder) implant market, DePuy is a leading
manufacturer in the United States and worldwide, with market shares of 29% and 26%,
respectively, representing U.S. sales of $15 million and worldwide sales of $21 million.
45%
40%
35%
30% Biomet
DePuy
25% Howmedica
Osteonics
20%
Richards
Zimmer
15%
10%
5%
0%
1990 1991 1992 1993 1994 1995
30%
25%
Biomet
20% Depuy
Howmedica
Intermedics
15%
J&J
Osteonics
10% Richards
Wright
Zimmer
5%
0%
1990 1991 1992 1993 1994 1995
The reconstructive device market is considered mature in the developed world, with
2% to 3% sales growth in the United States and 4% to 5% sales growth internationally.
We estimate 1996 sales growth of -2% in the United States and 3% internationally in the
hip implant market, and 5% in the United States and 7% internationally in the knee
implant market. Worldwide sales of implants for the extremities continue to grow
rapidly, but were only $80 million in 1995 and, therefore, do not significantly impact
overall sales growth in the reconstructive device market. In 1996 to date, DePuy’s
worldwide reconstructive device sales have increased 5%, with 10% unit increases
countering 5% mix and price declines.
Exhibit 21
70.0%
60.0%
50.0%
Knees
40.0%
Hips
30.0%
20.0%
10.0%
0.0%
Q1 93
Q2 93
Q3 93
Q4 93
Q1 94
Q2 94
Q3 94
Q4 94
Q1 95
Q2 95
Q3 95
Q4 95
Q1 96
Q2 96
Q3 96
Source: IMS America
Exhibit 22
Total
Fiscal Year Total Units Pricing Mix Shift Price
Spinal Implants
In 1993, DePuy entered the spinal implant market through a joint venture with DePuy Motech’s sales
Biedermann Motech GmbH of Germany, with the resulting company, DePuy Motech, 80% growth has been
owned by DePuy. DePuy Motech’s sales growth has been impressive: sales have soared impressive.
from $3.2 million in 1993 to a run rate of $50 million by the end of the third quarter of 1996.
The company has risen to the number-three position in the worldwide spinal implant
market, with an estimated 10% market share at the end of the third quarter of 1996.
DePuy Motech, like the rest of the spinal implant industry, is facing lawsuits
(approximately 600 lawsuits) relating to alleged conspiracy in the use of pedicle screws.
DePuy’s exposure is minimal, however, given that it was only named as a co-conspirator
and that the judge presiding over the pedicle screw litigation has made strong statements
in the past against the legitimacy of co-conspiracy claims.
Trauma
DePuy had 1995 estimated worldwide trauma sales of $49 million or about 5% of
the worldwide market, with U.S. sales of $26 million or about 6% of the U.S. market. In
1994, with the acquisition of ACE Medical, a manufacturer of titanium alloy trauma
products and external fixation devices, DePuy expanded its trauma franchise. The
company has done the easy work in growing trauma sales by picking up international
business through the introduction of trauma products in European markets and by selling
trauma products into its reconstructive device sales accounts. In Japan, DePuy ACE sells
through a distributor, but realizes excellent margins and has number-one or number-two
market share.
We believe that the best days for DePuy’s trauma business, which has not yet hit its The best days for
stride, are still ahead. The company recently established a dedicated U.S. trauma sales DePuy’s trauma
force of 50 representatives, potentially rivaling Synthes, the gorilla in the U.S. market business are still ahead.
with an estimated 35% share and a sales force of 65 to 70 sales representatives. DePuy’s
dedicated U.S. trauma sales force should help boost U.S. trauma sales, which have not
been spectacular. DePuy ACE suffered from supply constraints in 1995, however, these
have since been rectified and should no longer effect sales growth.
We expect DePuy ACE to achieve sales growth of 26% in 1997, 23% in 1998, 19%
in 1999, and 13% in 2000, as a result of market share gains in the United States and
continuing strong international growth. In the United States, we expect DePuy to gain
share from Zimmer, Howmedica, and Richards. Furthermore, the profitability of
DePuy’s trauma business should increase as DePuy ACE intends to bring all
manufacturing in-house over time, 70% of which is presently outsourced. We see a
longer-term threat in the entry of Stryker in the U.S. trauma market. With the acquisition
of Swiss-based Osteo Holdings and impending commercialization of OP-1, Stryker
could be a formidable competitor.
Other Products
DePuy’s other products include operating room supplies for use in reconstructive
joint surgery. This business suffered in 1996, as DePuy has focused on higher growth
product segments such as spinal implants, trauma, and sports medicine. We estimate
sales growth in other products of -4% for 1996 and -8% in 1997, with recovery to 6% in
1998, 7% in 1999, and 7% in 2000.
FY May 1995A 1996A 1997E Trauma Devices Cash per Share $1.10
Bone Growth Stimulators Total Debt $0
FY EPS $0.69 $0.77 $0.91
Arthroscopy Products
FY Rev. (mil.) $452.3 $535.2 $580.6
Craniomaxillofacial Products
FY Rev. Growth 21.2% 18.3% 8.5% Dow Jones 30 6560.91
Operating Room Supplies
Nasdaq Composite 1291.38
Net Income/Loss Options C/BIQ
Market Shares Avg. Daily FY95A $79.2 mil. Convertibles None
Cap Outstanding Volume FY96E $89.1 mil. Legal Disclosures a&f
$1.75 bil. 116.0 mil 100,000 FY97E $106.0 mil.
18.0
• Moderate size impedes growth through acquisition.
17.0
13.0
Millions
17.1
8.6
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov
INVESTMENT OVERVIEW
Biomet’s core businesses include reconstructive devices, internal and external
fixation devices, bone growth stimulators, arthroscopy products, craniomaxillofacial
products, orthopaedic support devices, and operating room supplies. When Biomet
reports its operating results, the company breaks out sales of reconstructive devices and
its Electro-Biology, Inc. (EBI) division, which sells bone growth stimulators and external
fixation devices, and consolidates all other sales in its “Other Products” category.
Exhibit 24
There are two main In our view, there are two main investment issues for Biomet: the company’s
investment issues: strategic position in the industry and the uncertainty surrounding its EBI business. With
strategic position and regard to the former, although a highly effective company in its execution, we do not
the EBI business. believe that Biomet provides a premier platform for growth/consolidation in the
orthopaedic industry. The titans of the industry, Zimmer (NYSE/BMY), Howmedica
(NYSE/PFE), and DePuy (NYSE/DPU), have significantly greater share in
reconstructive devices, are more diversified across product lines, and have greater
capacity for acquisition. We anticipate that their market share advantage should enable
them to win purchasing contracts, particularly in reconstructive devices, at the expense
of the mid-tier and small-tier companies, a trend that we expect to accelerate going
forward. We predict that this will hurt Biomet’s reconstructive device sales growth to an
increasing degree over time.
GROWTH DRIVERS
Biomet’s primary source of growth should come from continued strong ex-U.S. Biomet’s primary
sales growth. Ex-U.S. sales growth was 27.5% in fiscal 1995 and 27.7% in fiscal 1996, source of growth should
accounting for 24.0% of Biomet’s total sales in fiscal 1995 and 25.9% in fiscal 1996. come from continued
Although much of this growth came from acquisition of distributors, Biomet should be strong ex-U.S. sales
able to gain ex-U.S. share in reconstructive devices, currently at 4%, by continuing to growth.
enhance its surgeon relationships and market its clinical results with an increasingly
direct ex-U.S. presence. Going forward, however, we expect this strategy to be less
effective in the United States, and anticipate slowing progress in the U.S. device market.
We estimate Biomet reconstructive device sales growth of 9%, 10%, 8%, and 8% in
fiscal years 1997 to 2000, respectively.
EBI’s growth outlook is uncertain. We see downside risk from current businesses but EBI’s growth outlook is
upside potential from launch of a new spinal implant system, expected in February 1997. uncertain.
We expect growth in the bone growth stimulator business to remain sluggish through
fiscal 1997, as negative growth in the non-healing fractures segment largely offsets 20%
growth in the smaller spine segment. Furthermore, we expect growth in the external
fixation business to be flat in fiscal 1997 due to unfavorable comparisons with fiscal
1996, during which EBI reduced the ASPs for its Dynafix product line by close to 10%
relative to the Orthofix product line that it previously distributed.
Exhibit 25
As base business sales growth slows, Biomet will be able to use its cash flow to
make acquisitions, and to diversify into higher growth segments of the orthopaedic
products market.
Exhibit 26
PRODUCT SEGMENTS
Reconstructive Devices
Biomet is the number-five player in the hip implant market, with 11% share. The
company is the number-five player in the knee implant market, with 9% share. Biomet
also participates in the extremities implant market. From the beginning of 1993 to the
end of the third quarter of 1996, Biomet’s U.S. share in hips has increased from 8% to
11% and in knees from 6% to 9%.
Exhibit 27
Biomet’s strategy is to focus on providing superior service to the orthopaedic Biomet’s strategy is to
surgeon and to emphasize the clinical efficacy and cost-effectiveness of its implants, in focus on providing
order to justify price levels. The company has not signed any group purchasing contracts superior service to the
and has managed to achieve average annual price increases of 2% to 3% for its orthopaedic surgeon.
reconstructive devices, avoiding pricing pressure from mix shift and discounting.
However, Biomet sales growth in accounts that have contracts with other manufacturers
is only 5% to 6% versus 8% to 10% in accounts that are not part of group purchasing
contracts. The percentage of reconstructive device sales that are contract-based has
increased from 0% five years ago to about 15% in 1996.
Total
Total Units Pricing Mix Shift Price
1996A 19.9% 17.4%* 2.5% 0.3% 2.2%
EBI Division
Biomet’s EBI division manufactures and markets bone growth stimulators for
treatment of non-healing fractures and for adjunctive use in spinal fusion procedures to
increase the success rate for vertebral fusion, and also produces external fixation devices
Other Products
Biomet’s Other Products category includes devices manufactured and marketed by
subsidiaries, including Arthrotek and Walter Lorenz Surgical. These products include
internal fixation devices, operating room supplies, arthroscopy products, and
craniomaxillofacial products. Arthrotek manufactures and markets arthroscopy
products. Walter Lorenz Surgical manufactures and markets craniomaxillofacial
products. We estimate sales growth in Biomet’s Other Products category of 5% in fiscal
1997, with growth reduced by 6% due to transfer of the AOA product line to EBI.
Beyond fiscal 1997, we look for sales growth of 10%.
Biomet, through its Arthrotek subsidiary, offers a complete line of arthroscopy
products, including power instruments, manual instruments, visualization products, soft
tissue anchors, and procedure-specific instruments and implants. Arthrotek manufactures
and markets the IES 1000 system, a fully integrated arthroscopy system, the PowerPump
800, which enables compatibility with other arthroscopy shaver systems, and the One
Step ACL Guide System for use in anterior cruciate ligament reconstruction. While
Arthrotek sales growth has been flat, with increasing sales of disposables offsetting
decreasing sales of capital equipment, we expect Arthrotek sales growth to pick up as
capital equipment sales stabilize and disposables continue to grow.
Through its Walter Lorenz Surgical subsidiary, Biomet manufactures and markets a
full line of products for the craniomaxillofacial market. In February 1996, Walter Lorenz
received 510(k) and CE Mark approval to market the first resorbable plate and screw
system for craniomaxillofacial surgery in the United States and Europe. We expect
Walter Lorenz sales growth to remain in the teens, with enhanced profitability from
higher gross margins (60%, up from 45%) since the termination a supply agreement
with Leibinger. Walter Lorenz now buys instruments directly from Germany instead of
through Leibinger. Walter Lorenz may also make inroads into the dental implant market
in the future.
Biomet’s internal fixation devices include the Uniflex Nailing System, the
company’s largest selling fixation system. The Uniflex Nailing System is used for
internal fixation of femoral, tibial, and humeral fractures. It achieves intramedullary
fixation, whereby a “nail” is inserted into the central bone canal, increasing the
likelihood of fixation and reducing the probability of fracture site infection.
Biomet’s operating room supplies include surgical suction devices, filters, and
drapes. These products are less clinically differentiated, with sales growth most likely
reflecting overall market growth of about 10% in this segment of the orthopaedic
products market.
RECON TRAUMA SPINE ARTHROSCOPY SOFT TISSUE MAXILLOFACIAL BONE GRAFT BONE STIMULATION OSTEOBIOLOGICS
AcroMed x
Acumed x
Advanced Spine x
Aesculap x x x x x
Alphatec x x x
Arthrex x x
Avanta x
Bioelectron x
Biomet x x x x x x x
Bionix x x
Corin x x x x x
Danninger/Cross x
Encore x x x
Exactech x
Exogen x
Genesis x
Gliatech x
Implex x
Innovasive x x
Instrument Makar x x
Intermedics x x (ReGen)
Interpore x x
Johnson & Johnson x
Li Medical x
Link America x x
Norian x
Orquest x
Ortho Development x
Orthofix x x x
OrthoLogic x
Orthovita x
Osteotech x
OTI x
Raymedica x
Sofamor Danek x x x
Spine-Tech x
Synthes x x
U.S. Medical x
U.S. Surgical x
Whiteside Biomechanic x
Wright Medical x x x x x x
Howmedica
• Stronger ex-U.S.
• Not full line; primarily reconstructive products
• Established education as significant selling tool in 1980s
• Significant loss of share in all areas
Intermedics
• Sulzer strength lies ex-U.S.
• Not full-line; primarily reconstructive products
• Significant loss of manpower (shift of Cindrich et al. to Encore)
• Sister company, Calcitek, could provide dental/maxillofacial entry
Johnson & Johnson
• Reportedly mandated to become number one in global orthopaedic industry by
year 2000
• JMP acquisition was excellent match for J&J
• Not full-line; likely to buy its way into every other market
• Evokes tremendous respect and fear among competitors if the company swings
into action
Smith & Nephew
• Number-two worldwide, but relatively weak in reconstructive businesses
• Diminishing presence in spine
• Significant strength in arthroscopy, bracing and trauma (wound management
ex-U.S.)
• Best positioned of all companies to become a true “musculoskeletal” franchise
(from wound management to orthopaedics to maxillofacial to ENT, etc.)
Synthes
• The trauma company
• Trains and courts more than 2,000 surgeons annually
• Intensely loyal surgeon following
• Introduced the no-frills convention exhibit booth to orthopaedics
Zimmer
• Number-one worldwide
• Full line, with expansion into non-traditional orthopaedic areas (maxillofacial)
• Strong trauma franchise
• Significant restructuring internally and in the field (movement towards
megadistributorships)
• Conspicuously absent from spinal market
• Strong presence in Japan
1995 1Q96 2Q96 3Q96 4Q96 1996 % 1Q97 % 2Q97 % 3Q97 % 4Q97 % 1997 % 1998 % 1999 % 2000 %
# Fusions
3+ Level Fusions 4 1 1 1 1 4 4% 1 4% 1 4% 1 4% 1 4% 4 4% 4 7% 5 10% 5 10%
2 Level Fusions 27 7 7 7 7 28 4% 7 4% 7 4% 7 4% 7 4% 29 4% 31 7% 32 3% 34 8%
1 Level Fusions 42 10 11 11 11 43 4% 11 4% 11 4% 12 4% 12 4% 45 4% 48 7% 53 10% 59 10%
Revisions 4 1 1 1 1 4 4% 1 4% 1 4% 1 4% 1 4% 4 4% 4 7% 6 43% 8 23%
% Implant Usage
Institutional Research: The Skinny on the Skeleton 79
3+ Level Fusions 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100%
2 Level Fusions 98% 98% 98% 98% 98% 98% 98% 98% 98% 98% 98% 98% 98% 98%
1 Level Fusions 60% 60% 60% 61% 62% 61% 62% 63% 64% 65% 64% 68% 73% 73%
Revisions 95% 95% 95% 95% 95% 95% 95% 95% 95% 95% 95% 95% 95% 95%
Total 77% 77% 77% 78% 78% 77% 78% 79% 79% 80% 79% 81% 84% 84%
# Implants
Total 59 15 15 16 16 61 5% 15 5% 16 6% 17 6% 17 6% 65 6% 72 10% 81 13% 89 10%
80
1995 1Q96 2Q96 3Q96 4Q96 1996 % 1Q97 % 2Q97 % 3Q97 % 4Q97 % 1997 % 1998 % 1999 % 2000 %
Instrumentation as % Implants
3+ Level Fusions 100% 100% 100% 100% 100% 100% 99% 98% 98% 98% 98% 98% 98% 98%
2 Level Fusions 100% 100% 100% 98% 96% 98% 95% 94% 93% 92% 93% 87% 82% 78%
1 Level Fusions 100% 100% 100% 95% 90% 96% 87% 83% 79% 75% 81% 68% 56% 50%
Revisions 100% 100% 100% 90% 85% 94% 82% 78% 75% 70% 76% 50% 40% 30%
Total 100% 100% 100% 96% 93% 97% 91% 88% 86% 83% 87% 77% 67% 62%
Fusion Cages as % Implants
3+ Level Fusions 0% 0% 0% 0% 0% 0% 1% 2% 2% 2% 2% 2% 2% 2%
2 Level Fusions 0% 0% 0% 2% 4% 2% 5% 6% 7% 8% 7% 13% 18% 22%
1 Level Fusions 0% 0% 0% 5% 10% 4% 13% 17% 21% 25% 19% 32% 44% 50%
Revisions 0% 0% 0% 10% 15% 6% 18% 22% 25% 30% 24% 50% 60% 70%
Total 0% 0% 0% 4% 7% 3% 9% 12% 14% 17% 13% 23% 33% 38%
# Instrumentation Implants
Total 59 15 15 15 15 60 14 14 14 14 57 55 54 55
# Fusion Cage Implants
Total - - - 0.6 1.1 2 1.4 1.8 2.3 2.8 8 16.6 26.4 34.0
Cages/Implant 2.5 2.5 2.5 2.5 2.5 2.4 2.5 2.4 2.4
Instrumentation Implant $
3+ Level Fusions 10 2 3 3 3 10 3 3 3 3 11 12 13 14
2 Level Fusions 60 15 16 16 16 64 16 16 17 17 66 67 65 64
1 Level Fusions 48 12 13 13 13 51 12 12 12 12 48 47 46 43
Revisions 7 2 2 2 2 7 2 2 2 1 6 4 5 4
Total 124 31 33 34 33 131 32 33 33 33 131 130 128 126
Fusion Cage $ $ 3 $ 5 $ 8 $ 6 $ 8 $ 10 $ 12 $ 37 $ 75 100% $ 116 55% $ 145 25%
US Lumbar Implant $ $ 124 $ 31 $ 33 $ 36 $ 38 $ 139 12% $ 38 $ 41 $ 44 $ 46 $ 168 21% $ 204 22% $ 244 19% $ 271 11%
Appendix F: Spine Market Model
Hambrecht & Quist LLC Market Shares by Product Category and Company, 1995-2000 R. Faulkner/D.Shoaib
1995 1Q96 2Q96 3Q96 4Q96 1996 % 1Q97 % 2Q97 % 3Q97 % 4Q97 % 1997 % 1998 % 1999 % 2000 %
Price Assumptions ($000)
$/Instrumented 3 Level 2.5 2.5 2.6 2.6 2.6 2.6 2.7 2.7 2.7 2.8 2.8 2.7
$/Instrumented 2 Level 2.3 2.3 2.4 2.4 2.4 2.4 2.5 2.5 2.5 2.5 2.5 2.5
$/Instrumented 1 Level 1.9 2.0 2.0 2.0 2.0 2.1 2.1 2.1 2.1 2.1 2.1 2.0
Y/Y Price Change 4% 5% 5% 5% 5% 4% 4% 4% 1% 0% -3%
$/ Cage (2/level) 1.8 1.8 1.8 1.8 1.8 1.8 1.8 1.8 1.8 1.8 1.8 1.7
1995 1Q96 2Q96 3Q96 4Q96 1996 % 1Q97 % 2Q97 % 3Q97 % 4Q97 % 1997 % 1998 % 1999 % 2000 %
Lumbar Procedures 48 12 13 13 13 51 7% 13 7% 13 7% 14 7% 14 7% 55 7% 58 6% 62 6% 65 6%
% Implant Usage 50% 51% 51% 52% 52% 53% 53% 54% 54% 56% 57% 59%
Procedures w/Implant 24 6 6 7 7 26 10% 7 7 7 8 11% 29 11% 32 10% 35 9% 38 9%
Instrumentation % 98% 98% 98% 98% 98% 98% 98% 97% 97% 95% 90% 85%
Fusion Cage % 2% 2% 2% 2% 2% 2% 2% 3% 3% 5% 10% 15%
Asia and Other Non US/Europe Lumbar Spinal Implant Market Projections 12/12/1996
1995 1Q96 2Q96 3Q96 4Q96 1996 % 1Q97 % 2Q97 % 3Q97 % 4Q97 % 1997 % 1998 % 1999 % 2000 %
Total $ $ 46 $ 14 $ 14 $ 15 $ 15 $ 57 25% $ 17 0.25 $ 17 0.24 $ 18 0.24 $ 18 23% $ 71 24% $ 85 20% $ 100 18% $ 115 15%
Sofamor Danek @ 50% 23 7 7 7 7 29 9 9 9 9 35 43 50 58
AcroMed @20% 9 3 3 3 3 11 3 3 4 4 14 17 20 23
Stryker @ 5% 2 1 1 1 1 3 1 1 1 1 4 4 5 6
DePuy @5% 2 1 1 1 1 3 1 1 1 1 4 4 5 6
Other % 9 3 3 3 3 11 3 3 4 4 14 17 20 23
1995 1Q96 2Q96 3Q96 4Q96 1996 % 1Q97 % 2Q97 % 3Q97 % 4Q97 % 1997 % 1998 % 1999 % 2000 %
Worldwide Total ($mm) $ 226 $ 60 $ 63 $ 67 $ 70 $ 261 15% $ 72 $ 76 $ 81 $ 84 $ 314 20% $ 375 20% $ 441 18% $ 492 12%
Sofamor Danek 107 28 29 29 29 115 7% 30 30 31 31 122 6% 128 4% 136 7% 148 9%
AcroMed 44 12 12 13 13 50 12% 13 13 13 14 53 7% 54 2% 57 5% 59 3%
Stryker 12 3 3 3 4 13 15% 4 4 4 4 16 16% 21 35% 25 19% 30 19%
DePuy * 15 4 5 6 6 21 39% 6 7 7 7 28 34% 33 18% 35 7% 36 3%
Synthes (US only) 17 5 5 5 6 21 21% 5 6 6 6 22 6% 22 -1% 22 -1% 21 -2%
Spine-Tech 1 0 0 0 5 5 nm 6 7 8 9 29 nm 50 71% 77 55% 94 21%
US Surgical 0 0 0 0 1 1 nm 1 1 3 4 9 nm 27 213% 44 62% 54 24%
Biomet 0 0 0 0 0 0 nm 0 0 0 0 0.7 5 8 9
Other 30 8 8 11 8 35 16% 8 8 9 9 35 -1% 40 16% 45 12% 50 11%
Total Sales 214 229 205 224 872 218 225 224 246 912 241 254 252 273 1,021 273 291 292 329 1,185
Total Growth 44% 48% 18% 11% 28% 2% (1%) 9% 10% 5% 11% 13% 13% 11% 12% 13% 14% 16% 20% 16%
Sales Ex-Matsu 182 195 185 205 767 205 214 213 236 868 232 246 244 265 988 265 282 283 320 1,150
Growth Ex-Matsu 22% 27% 17% 17% 21% 13% 10% 15% 15% 13% 13% 15% 15% 12% 14% 14% 15% 16% 20% 16%
Fx Impact 1% 1% 1% (0%) 1% (2%) (3%) (3%) (1%) (2%) (1%) (0%) 0% 0% (0%) 0% 0% 0% 0% 0%
Growth Ex-Matsu/Fx 21% 26% 16% 17% 20% 14% 13% 18% 17% 15% 15% 15% 15% 12% 14% 14% 15% 16% 20% 16%
Acquired Sales 14 17 4 2 36 11 11 10 15 47 12 13 14 7 47 6 6 5 5 23
Acquired Growth 9% 11% 2% 1% 5% 5% 5% 5% 6% 5% 6% 6% 6% 3% 5% 3% 2% 2% 2% 2%
Base Business Growth 12% 15% 14% 16% 15% 9% 8% 13% 10% 10% 9% 9% 9% 9% 9% 11% 12% 14% 19% 14%
Appendix J: Stryker Sales Model
1Q 95 2Q 95 3Q 95 4Q 95 1995 1Q 96 2Q 96 3Q 96
Geography
Domestic 112 118 118 129 477 134 139 143
Y/Y % 19% 20% 15% 18% 18% 19% 18% 22%
International 102 110 88 95 395 84 86 80
Y/Y % 88% 98% 22% 0% 43% (18%) (22%) (8%)
International Ex-Matsu. 70 77 67 76 290 71 75 70
Y/Y % 21% 12% 24% 2% (3%) 4%
Japan 74 80 58 64 275 51 51 43
Y/Y % 173% 176% 30% (6%) 63% (31%) (36%) (26%)
Y/Y % Ex-FX 157% 162% 31% (2%) 57% (7%) (6%) (14%)
Other International 28 31 31 31 120 33 35 37
Y/Y % 3% 14% 13% 15% 11% 19% 14% 22%
Y/Y % Ex-FX 18% 24% 19% 19% 11% 14% 7% 18%
Total 214 229 205 224 872 218 225 224
Y/Y % 44% 48% 18% 10% 28% 2% (1%) 9%
KNOWLEDGE ENTERPRISES, Inc., based in Chagrin Falls, Ohio, is a consulting firm specializing in the orthopaedic
industry. Its principals, John Engelhardt and Shirley Engelhardt have served in industry in marketing, product develop-
ment, and general management capacities. KNOWLEDGE ENTERPRISES, Inc. serves the needs of large and small
orthopaedic industry players for market analysis, due diligence, and business development.
KNOWLEDGE ENTERPRISES, Inc. is not a licensed investment firm and claims no responsibility for investment rec-
ommendations contained herein. Investment recommendations are the sole responsibility of Hambrecht & Quist, LLC.
Total Y-Y Gross Oper Oper Pretax Y-Y Tax Net Y-Y Net Y-Y
Sales Chge Margin Income Margin Income Chge Taxes Rate Income Chge Margin EPS Chge Shares
$M % % $M % $M % $M % $M % % $ % M
1994
Q1 148.8 10.0% 54.6% 25.4 17% 28.0 20.0% 10.6 38.0% 17.3 20.0% 11.7% $0.18 19.8% 96.8
Q2 154.2 10.2% 54.3% 25.2 16% 27.4 21.7% 10.4 38.0% 17.0 21.5% 11.0% $0.18 21.5% 96.7
Q3 174.3 27.3% 55.4% 29.2 17% 29.7 31.7% 11.9 40.0% 16.7 19.6% 9.6% $0.17 19.7% 96.7
Q4 204.6 40.9% 58.7% 40.6 20% 42.5 53.5% 17.8 40.0% 21.3 20.0% 10.4% $0.22 20.1% 96.7
1994 681.9 22.4% 56.0% 120.5 18% 127.6 32.8% 50.8 39.8% 76.8 27.6% 11.3% $0.79 27.5% 96.7
1995
Q1 214.0 43.9% 59.0% 42.0 20% 42.8 52.9% 18.0 42.1% 20.7 19.4% 9.7% $0.21 19.4% 96.8
Q2 228.5 48.2% 57.3% 38.6 17% 40.2 46.6% 16.9 42.0% 20.4 20.0% 8.9% $0.21 19.8% 96.9
Q3 205.4 17.8% 56.8% 34.6 17% 35.9 21.0% 14.4 40.0% 20.1 20.3% 9.8% $0.21 19.9% 97.0
Q4 224.1 9.5% 57.4% 42.0 19% 44.0 3.8% 17.6 40.0% 25.7 20.4% 11.5% $0.26 20.0% 97.1
1995 872.0 27.9% 57.6% 157.2 18% 163.0 27.8% 66.9 41.0% 86.9 13.2% 10.0% $0.90 12.9% 96.9
1996
Q1 217.6 1.7% 58.9% 39.9 18% 41.8 -2.4% 15.9 38.0% 25.0 20.9% 11.5% $0.26 20.5% 97.1
Q2 225.4 -1.4% 59.0% 38.6 17% 41.1 2.1% 15.6 38.0% 24.5 20.0% 10.9% $0.25 20.2% 96.7
Q3 223.6 8.9% 57.8% 36.8 16% 39.0 8.5% 14.8 38.0% 24.2 20.0% 10.8% $0.25 20.3% 96.7
Q4 E 246.0 9.8% 59.0% 46.7 19% 49.2 11.8% 18.7 38.0% 30.5 18.9% 12.4% $0.32 19.4% 96.7
1996 E 912.6 4.7% 58.7% 162.0 18% 171.1 4.9% 65.0 38.0% 104.2 19.9% 11.4% $1.08 20.0% 96.8
1997
Q1 E 241.7 11.1% 59.0% 45.4 19% 48.2 15.4% 18.3 38.0% 29.9 19.4% 12.4% $0.31 19.9% 96.8
Q2 E 251.5 11.6% 59.0% 44.8 18% 47.3 15.1% 18.0 38.0% 29.3 19.7% 11.7% $0.30 19.6% 96.8
Q3 E 253.7 13.5% 59.0% 44.4 18% 46.7 19.8% 17.7 38.0% 29.0 19.9% 11.4% $0.30 19.7% 96.9
Q4 E 274.5 11.6% 59.5% 56.0 20% 58.7 19.2% 22.3 38.0% 36.4 19.2% 13.3% $0.38 19.0% 96.9
1997 E 1021.4 11.9% 59.1% 190.6 200.9 17.4% 76.3 38.0% 124.5 19.5% 12.2% $1.29 19.5% 96.8
1998
Q1 E 270.3 11.8% 59.2% 55.7 21% 58.2 20.7% 22.1 38.0% 36.1 20.7% 13.3% $0.37 20.5% 97.0
Q2 E 285.0 13.3% 59.2% 54.7 19% 57.3 21.3% 21.8 38.0% 35.4 20.9% 12.4% $0.37 20.7% 97.0
Q3 E 299.8 18.2% 59.0% 54.0 18% 56.7 21.3% 21.5 38.0% 34.9 20.7% 11.7% $0.36 20.4% 97.1
Q4 E 329.5 20.0% 59.7% 68.9 21% 71.5 21.8% 27.2 38.0% 44.0 20.9% 13.4% $0.45 20.7% 97.1
1998 E 1184.6 16.0% 59.3% 233.2 20% 243.6 21.3% 92.6 38.0% 150.5 20.8% 12.7% $1.55 20.6% 97.0
(a) H&Q LLC maintains a market in this stock. (f) Options are available on this issue.
1993 466.7 11.1% 67.5% 129.6 27.8% 126.9 30.3% 57.0 44.9% 72.2 33.5% 15.5% $0.80 33.5% 90.0
1994
Q1 129.9 NA 66.2% 35.9 27.6% 35.6 NA 15.7 44.1% 20.7 NA 15.9% $0.23 NA 90.0
Q2 137.3 NA 68.1% 39.4 28.7% 38.9 NA 17.1 44.0% 22.6 NA 16.5% $0.25 NA 90.0
Q3 136.0 NA 67.3% 34.9 25.7% 34.3 NA 15.1 44.0% 19.8 NA 14.6% $0.22 NA 90.0
Q4 148.6 NA 72.6% 41.0 27.6% 40.8 NA 17.9 43.9% 23.7 NA 15.9% $0.26 NA 90.0
1994 551.8 18.2% 68.7% 151.2 27.4% 149.6 17.9% 65.8 44.0% 86.8 20.2% 15.7% $0.96 20.2% 90.0
1995
Q1 161.1 24.0% 67.3% 45.1 28.0% 44.3 24.4% 18.8 42.4% 26.3 27.1% 16.3% $0.29 27.1% 90.0
Q2 162.1 18.1% 67.8% 44.1 27.2% 43.6 12.1% 19.2 44.0% 25.2 11.5% 15.5% $0.28 11.5% 90.0
Q3 148.4 9.1% 68.4% 36.7 24.7% 35.8 4.4% 16.1 45.0% 20.3 2.5% 13.7% $0.23 2.5% 90.0
Q4 164.9 11.0% 70.6% 44.4 26.9% 41.0 0.5% 18.6 45.4% 23.1 (2.5%) 14.0% $0.26 (2.5%) 90.0
1995 636.5 15.3% 68.6% 170.3 26.8% 164.7 10.1% 72.7 44.1% 94.9 9.3% 14.9% $1.05 9.3% 90.0
1996
Q1 173.1 7.4% 69.2% 48.3 27.9% 46.9 5.9% 20.2 43.1% 27.4 4.2% 15.8% $0.30 4.2% 90.0
Q2 175.9 8.5% 69.8% 49.4 28.1% 48.8 11.9% 21.1 43.2% 28.2 11.9% 16.0% $0.31 11.9% 90.0
Q3 167.3 12.7% 70.9% 44.0 26.3% 42.3 18.1% 18.2 43.1% 24.0 18.3% 14.4% $0.27 18.3% 90.0
Q4 E 182.0 10.4% 70.8% 48.1 26.5% 47.9 16.9% 20.7 43.1% 27.2 17.7% 14.9% $0.28 10.6% 95.7
1996 E 698.3 9.7% 70.2% 189.8 27.2% 185.9 12.9% 80.2 43.1% 106.8 12.5% 15.3% $1.17 10.8% 91.4
1997
Q1 E 188.9 9.1% 71.0% 50.9 27.0% 51.4 9.6% 22.2 43.1% 29.2 6.6% 15.5% $0.30 (2.7%) 98.6
Q2 E 193.8 10.2% 71.1% 52.5 27.1% 53.0 8.6% 22.9 43.1% 30.1 6.8% 15.5% $0.31 (2.5%) 98.6
Q3 E 182.8 9.3% 71.2% 49.9 27.3% 50.4 19.3% 21.7 43.1% 28.6 19.2% 15.7% $0.29 8.8% 98.6
Q4 E 199.0 9.3% 71.2% 55.2 27.7% 55.7 16.2% 24.0 43.1% 31.6 16.3% 15.9% $0.32 13.0% 98.6
1997 E 764.5 9.5% 71.1% 208.6 27.3% 210.6 13.3% 90.8 43.1% 119.6 12.0% 15.6% $1.21 3.8% 98.6
1998
Q1 E 206.5 9.3% 71.3% 58.0 28.1% 58.5 13.8% 25.2 43.1% 33.2 13.7% 16.1% $0.34 13.6% 98.6
Q2 E 214.9 10.9% 71.3% 60.5 28.2% 61.0 15.1% 26.3 43.1% 34.6 14.9% 16.1% $0.35 14.8% 98.6
Q3 E 201.8 10.4% 71.4% 56.8 28.2% 57.3 13.7% 24.7 43.1% 32.4 13.4% 16.1% $0.33 13.4% 98.6
Q4 E 218.8 9.9% 71.5% 62.3 28.5% 62.8 12.8% 27.1 43.1% 35.5 12.3% 16.2% $0.36 12.3% 98.6
1998 E 842.0 10.1% 71.4% 237.7 28.2% 239.7 13.8% 103.3 43.1% 135.7 13.5% 16.1% $1.38 13.5% 98.6
1999 E 929.5 10.4% 71.6% 266.5 28.7% 268.5 12.0% 115.7 43.1% 152.0 12.0% 16.4% $1.54 12.0% 98.6
2000 E 1021.5 9.9% 71.8% 297.1 29.1% 299.1 11.4% 128.9 43.1% 169.3 11.4% 16.6% $1.72 11.4% 98.6
Y-Y Gross Oper Oper Pretax Y-Y Tax Net Y-Y Net Y-Y
Sales Growth Margin SG&A SG&A Inc Mgn Inc Growth Taxes Rate Inc Growth Mgn EPS Growth Shares
$M % % $ % $M % $M % $M % $M % % $ % M
___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___
1991 75.5 N/A 72.9% 31 40.8% 19.2 25.5% 19.9 0.0% 7.5 37.5% 12.4 0.0% 16.4% $0.53 0.0% 23.4
1992 121.0 60.2% 79.2% 56 46.5% 31.7 26.2% 32.6 64.1% 12.0 36.8% 20.6 66.0% 17.0% $0.84 58.0% 24.6
1993
Q1 34.6 N/A 78.2% 15 43.2% 9.5 27.4% 9.5 3.6 37.2% 6.0 17.3% $0.24 24.7
Q2 40.3 N/A 77.3% 18 43.9% 10.5 26.1% 10.8 3.8 35.4% 6.9 17.3% $0.28 24.7
Q3 42.6 N/A 78.3% 18 41.2% 12.7 29.9% 12.4 4.4 35.7% 8.0 18.7% $0.32 24.7
Q4 44.4 N/A 77.5% 18 39.8% 13.8 31.2% 13.5 4.5 33.2% 9.0 20.2% $0.36 24.7
1993 161.8 33.7% 77.8% 68 41.9% 46.6 28.8% 46.2 41.6% 16.3 35.2% 29.9 44.8% 18.5% $1.21 44.0% 24.7
1994
Q1 39.1 13.0% 79.5% 16 42.2% 12.1 31.0% 12.5 31.0% 4.5 35.6% 8.0 34.1% 20.6% $0.32 33.5% 24.8
Q2 38.1 (5.5%) 78.9% 17 45.3% 10.1 26.6% 10.6 (2.0%) 3.0 28.6% 7.5 7.7% 19.7% $0.30 8.4% 24.6
Q3 42.2 (0.9%) 77.2% 19 45.6% 10.4 24.7% 10.3 (17.0%) 1.2 11.4% 9.1 14.8% 21.6% $0.37 14.8% 24.7
Q4 42.4 (4.5%) 77.2% 22 51.3% 8.0 18.8% 8.3 (38.0%) 0.8 9.7% 7.5 (16.2%) 17.8% $0.31 (14.8%) 24.3
1994 161.7 (0.1%) 78.2% 75 46.2% 40.6 25.1% 41.7 (9.7%) 9.5 22.7% 32.2 7.7% 19.9% $1.31 8.2% 24.6
1995
Q1 43.9 12.4% 77.2% 20 46.5% 10.3 23.3% 10.5 (16.2%) 2.5 23.4% 8.0 (1.0%) 18.1% $0.32 (2.5%) 25.2
Q2 43.5 14.2% 78.9% 22 49.8% 9.3 21.4% 10.3 (2.1%) 2.3 21.9% 8.0 7.3% 18.5% $0.32 5.1% 25.1
Q3 47.2 11.9% 79.0% 22 47.3% 11.5 24.4% 10.9 6.2% 2.2 20.5% 8.6 (5.6%) 18.3% $0.34 (6.8%) 25.0
Q4 54.0 27.6% 79.6% 26 47.9% 13.6 25.1% 12.8 53.8% 2.6 20.2% 9.8 30.6% 18.2% $0.38 23.3% 25.7
1995 188.6 16.7% 78.7% 90 47.8% 44.7 23.7% 44.6 6.9% 9.5 21.4% 34.4 7.0% 18.3% $1.36 4.2% 25.2
1996
Q1 54.2 23.4% 80.4% 26 47.9% 14.0 25.8% 14.2 35.3% 3.6 25.3% 10.2 28.0% 18.8% $0.39 23.4% 26.1
Q2 56.8 30.7% 82.9% 27 47.1% 16.4 28.8% 15.7 51.5% 4.6 29.4% 10.6 32.4% 18.7% $0.41 28.0% 26.0
Q3 63.2 33.9% 83.6% 31 48.4% 18.0 28.4% 16.5 51.0% 5.0 30.5% 11.0 27.9% 17.4% $0.42 21.9% 26.1
Q4 E 65.5 21.2% 83.6% 32 48.5% 18.6 28.3% 17.3 34.6% 5.3 30.5% 11.6 18.0% 17.7% $0.44 15.8% 26.2
1996 E 239.7 27.1% 82.7% 115 48.0% 66.9 27.9% 63.6 42.7% 18.5 29.1% 43.4 26.2% 18.1% $1.66 22.0% 26.1
1997
Q1 67.0 23.6% 83.4% 31 47.0% 19.9 29.7% 18.5 30.5% 6.0 32.5% 12.1 18.4% 18.0% $0.46 18.5% 26.1
Q2 E 69.5 22.3% 83.4% 33 47.0% 20.6 29.7% 19.2 22.7% 6.3 32.5% 12.5 17.7% 18.0% $0.48 16.7% 26.2
Q3 E 72.0 13.9% 83.4% 33 46.0% 22.1 30.7% 20.7 25.5% 6.7 32.5% 13.5 22.2% 18.7% $0.51 22.3% 26.2
Q4 E 74.0 13.0% 83.4% 33 45.0% 23.5 31.7% 22.1 27.7% 7.2 32.5% 14.4 23.8% 19.4% $0.55 23.4% 26.3
1997 E 282.5 17.8% 83.4% 131 46.2% 86.1 30.5% 80.5 26.5% 26.2 32.5% 52.4 20.6% 18.6% $2.00 20.3% 26.2
1998 E 316.5 12.0% 81.0% 141 44.5% 94.3 29.8% 93.7 16.4% 30.0 32.0% 63.7 21.6% 20.1% $2.40 20.2% 26.5
Y-Y Gross Oper Oper Pretax Pretax Tax Net Net Ongoing Fully
Sales Chge Margin SG&A Income Margin Income Growth Tax Rate Tax Inc. Margin EPS Taxed Shrs
$M % % % $M % $M % $M % % $M % $ EPS $ M
___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___
1992 0.3 N/A 88% 274% (1.4) nm (1.4) 0% 0.0 0% 0% (1.4) nm n/a n/a n/a
n/a
1993 2.0 5% 80% 82% (0.7) nm (0.0) nm 0.0 0% 0% (0.0) nm n/a n/a n/a
1994
Q1 0.9 N/A 71% 65% (0.1) nm (0.1) nm 0.0 0% 0% (0.1) nm n/a n/a n/a
Q2 1.1 N/A 74% 62% (0.1) nm (0.1) nm 0.0 0% 0% (0.1) nm n/a n/a n/a
Q3 1.2 N/A 73% 47% (0.1) nm (0.1) nm 0.0 0% 0% (0.1) nm n/a n/a n/a
Q4 1.2 N/A 75% 51% (0.2) nm (0.2) nm 0.0 0% 0% (0.2) nm n/a n/a n/a
1994 4.4 120% 73% 56% (0.6) nm (0.6) nm 0.0 0% 0% (0.6) nm ($0.09) n/a 6.6
1995
Q1 1.6 70% 62% 44% (0.1) nm (0.1) nm 0.0 0% 0% (0.1) (6%) ($0.01) n/a 6.6
Q2 1.7 55% 63% 48% (0.1) nm (0.1) nm 0.0 0% 0% (0.1) (6%) ($0.01) n/a 6.7
Q3 2.1 73% 76% 63% (0.2) nm 0.2 nm 0.0 0% 0% 0.2 8% $0.02 n/a 9.5
Q4 2.2 84% 74% 58% (0.1) nm 0.3 nm 0.0 0% 0% 0.3 14% $0.03 n/a 9.7
1995 7.5 71% 69% 54% (0.6) nm 0.3 nm 0.0 0% 0% 0.3 4% $0.03 n/a 8.1
1996
Q1 1.4 (7%) 61% 84% (0.8) nm (0.4) nm 0.0 0% 0% (0.4) (25%) ($0.03) n/a 9.7
Q2 1.5 (12%) 62% 99% (1.0) nm (0.6) nm 0.0 0% 0% (0.6) (39%) ($0.06) n/a 9.9
Q3 1.5 (27%) 69% 151% (1.7) nm (1.4) nm 0.0 0% 0% (1.4) (95%) ($0.15) n/a 9.9
Q4 E 6.0 176% 72% 65% (0.3) nm (0.1) nm 0.0 0% 0% (0.1) (1%) ($0.01) n/a 10.0
1996 E 10.5 39% 69% 85% (3.8) nm (2.5) nm 0.0 0% 0% (2.5) (24%) ($0.25) n/a 9.9
1997
Q1 E 7.0 384% 76% 67% (0.2) (2%) 0.2 nm 0.0 25% 25% 0.1 2% $0.01 $0.01 10.7
Q2 E 8.0 432% 78% 60% 0.5 7% 0.9 nm 0.2 25% 25% 0.7 8% $0.06 $0.05 10.9
Q3 E 9.5 524% 79% 55% 1.2 13% 1.7 nm 0.4 25% 25% 1.3 13% $0.12 $0.10 11.1
Q4 E 11.0 83% 80% 49% 2.3 21% 2.6 nm 0.7 25% 25% 2.0 18% $0.17 $0.14 11.3
1997 E 35.5 239% 78% 56% 3.9 11% 5.4 nm 1.3 25% 25% 4.0 11% $0.36 $0.30 11.0
1998
Q1 E 12.0 71% 80% 51% 2.2 18% 2.5 nm 0.8 30% 30% 1.8 15% $0.15 $0.14 11.4
Q2 E 13.2 64% 80% 50% 2.5 19% 2.8 nm 0.8 30% 30% 2.0 15% $0.17 $0.15 11.5
Q3 E 14.4 51% 81% 49% 3.0 21% 3.3 nm 1.0 30% 30% 2.3 16% $0.20 $0.18 11.6
Q4 E 15.6 41% 81% 48% 3.4 22% 3.7 nm 1.1 30% 30% 2.6 17% $0.22 $0.20 11.6
1998 E 55.0 55% 81% 49% 11.1 20% 12.3 129% 3.7 30% 30% 8.6 16% $0.75 $0.66 11.5
1999 E 85.0 55% 81% 48% 19.7 23% 20.3 65% 7.7 38% 38% 12.6 15% $1.05 $1.05 13.7
2000 E 105.0 24% 81% 45% 27.0 26% 27.8 37% 10.6 38% 38% 17.2 16% $1.35 $1.35 14.0
* Total available to fund operating deficit includes virtually all of these line items.
a) Hambrecht & Quist LLC maintains a market in this stock.
1995
Q1 96.2 10.7% 69.0% 26.0 27.1% 27.4 17.4% 10.3 37.6% 17.1 11.6% 17.8% $0.15 12.6% 114.4
Q2 106.9 18.3% 69.2% 29.3 27.4% 30.9 21.5% 11.5 37.2% 19.4 15.6% 18.2% $0.17 15.9% 115.0
Q3 120.7 26.2% 67.9% 31.2 25.9% 32.7 16.5% 12.2 37.2% 20.5 13.6% 17.0% $0.18 12.8% 116.1
Q4 128.5 27.9% 68.3% 32.5 25.3% 35.2 17.0% 13.1 37.2% 22.1 12.8% 17.2% $0.19 11.5% 116.3
1995 452.3 21.2% 68.6% 119.0 26.3% 126.3 18.0% 47.1 37.3% 79.2 13.4% 17.5% $0.69 13.1% 115.5
509.5 CY95 $0.73
1996
Q1 127.2 32.2% 67.6% 28.8 22.7% 30.9 12.5% 12.2 39.5% 18.6 9.0% 14.7% $0.16 8.1% 115.4
Q2 133.0 24.5% 67.3% 34.7 26.1% 36.5 18.2% 13.8 37.8% 22.7 17.1% 17.1% $0.20 16.7% 115.4
Q3 133.5 10.6% 67.1% 35.7 26.7% 37.2 13.8% 13.7 36.8% 23.5 14.4% 17.6% $0.20 15.0% 115.5
Q4 141.4 10.1% 67.7% 38.0 26.9% 40.1 13.7% 15.8 39.5% 24.2 9.5% 17.1% $0.21 10.3% 115.5
1996 535.2 18.3% 67.4% 137.3 25.7% 144.7 14.6% 55.6 38.4% 89.1 12.5% 16.7% $0.77 12.6% 115.5
556.1 CY96 $0.85
1997
Q1 137.2 7.8% 67.6% 36.3 26.5% 38.7 25.4% 14.6 37.8% 24.1 29.2% 17.6% $0.21 27.8% 116.6
Q2 144.0 8.2% 67.8% 39.4 27.4% 41.6 13.8% 15.4 37.0% 26.2 15.2% 18.2% $0.23 14.6% 116.0
Q3 E 145.2 8.8% 68.0% 40.2 27.7% 42.7 14.9% 15.8 37.0% 26.9 14.6% 18.5% $0.23 13.4% 116.7
Q4 E 154.2 9.0% 68.2% 43.2 28.0% 45.7 14.0% 16.9 37.0% 28.8 18.8% 18.7% $0.25 17.5% 116.7
1997 E 580.6 8.5% 67.9% 159.2 27.4% 168.7 16.6% 62.7 37.2% 106.0 18.9% 18.3% $0.91 17.8% 116.5
611.6 CY97 $0.98
1998
Q1 E 150.6 9.8% 68.5% 42.6 28.3% 45.1 16.6% 16.7 37.0% 28.4 18.0% 18.9% $0.24 17.8% 116.8
Q2 E 161.6 12.2% 68.8% 46.2 28.6% 48.7 17.1% 18.0 37.0% 30.7 17.2% 19.0% $0.26 16.4% 116.8
Q3 E 160.0 10.2% 69.1% 46.2 28.9% 48.7 14.1% 18.0 37.0% 30.7 14.1% 19.2% $0.26 13.9% 116.9
Q4 E 169.5 10.0% 69.5% 49.7 29.3% 52.2 14.2% 19.3 37.0% 32.9 14.2% 19.4% $0.28 14.0% 116.9
1998 E 641.7 10.5% 69.0% 184.7 28.8% 194.7 15.5% 72.1 37.0% 122.7 15.8% 19.1% $1.05 15.4% 116.8
670.8 CY98 $1.12
1999
Q1 E 164.9 9.5% 69.7% 48.7 29.5% 51.2 13.3% 18.9 37.0% 32.2 13.3% 19.5% $0.28 13.2% 117.0
Q2 E 176.4 9.2% 69.9% 52.4 29.7% 54.9 12.7% 20.3 37.0% 34.6 12.7% 19.6% $0.30 12.5% 117.0
Q3 E 174.3 9.0% 70.0% 51.9 29.8% 54.4 11.7% 20.1 37.0% 34.3 11.7% 19.7% $0.29 11.6% 117.1
Q4 E 184.6 8.9% 70.0% 55.0 29.8% 57.5 10.3% 21.3 37.0% 36.2 10.3% 19.6% $0.31 10.1% 117.1
1999 E 700.3 9.1% 69.9% 208.0 29.7% 218.0 12.0% 80.7 37.0% 137.4 12.0% 19.6% $1.17 11.8% 117.0
2000 E 759.6 8.5% 70.5% 230.2 30.3% 240.2 10.2% 88.9 37.0% 151.3 10.2% 19.9% $1.29 10.0% 117.2
(a) H&Q LLC maintains a market in this stock. (f) Options are available on this issue.
Total Q-Q Y-Y Gross Oper. Oper Interest Other Pretax Y-Y Net Y-Y Net Fully Y-Y
Sales Chge Chge Margin SG&A SG&A R&D R&D Income Margin Income Expenses Income Chge Tax Tax Income Chge Margin EPS Taxed Chge Shares
$M % % % $M % $M % $M % $M $M $M % $M % $M % % $ EPS $ % M
1993 0.3 NA 51% 1.1 341% 2.8 500% (3.7) NM - - (3.3) NM 0.0 0% (3.3) NM NM (0.51) n/a NM 6.5
1994 5.0 NM 100% 5.6 113% 2.8 56% (4.8) NM - - (4.5) NM 0.0 0% (4.5) NM NM (0.65) n/a 6.9
1995
Q1 2.5 26% 383% 78% 2.3 93% 0.6 25% (1.1) NM - - (0.9) NM 0.0 0% (0.9) NM NM (0.07) n/a NM 14.3
Q2 3.1 22% 182% 79% 2.6 85% 0.5 17% (0.7) NM - - (0.6) NM 0.0 0% (0.6) NM NM (0.04) n/a NM 15.0
Q3 4.1 32% 199% 80% 3.0 74% 0.5 11% (0.2) NM - - (0.1) NM 0.0 0% (0.1) NM NM (0.01) n/a NM 15.0
Q4 5.0 24% 153% 79% 3.4 67% 0.5 10% 0.1 2% - - 0.3 NM 0.0 0% 0.3 NM 6% 0.02 0.01 NM 17.9
1995 14.7 196% 79% 11.3 77% 2.1 15% (1.9) NM - - (1.4) NM 0.0 0% (1.4) NM NM (0.09) n/a NM 15.5
1996
Q1 6.8 34% 169% 83% 4.4 65% 0.6 8% 0.7 10% 0.3 - 0.9 NM 0.02 0% 0.9 NM 14% 0.04 0.03 NM 20.8
Q2 7.9 17% 157% 84% 5.5 70% 0.5 7% 0.6 7% 0.9 - 1.5 NM 0.02 0% 1.5 NM 19% 0.06 0.04 NM 24.8
Q3 10.4 32% 157% 82% 8.5 82% 0.5 5% (0.6) -5% 1.1 - 0.5 NM 0.00 0% 0.5 NM 4% 0.02 0.01 NM 25.8
Q4 E 16.3 57% 224% 73% 11.5 70% 0.6 4% (0.2) -1% 0.7 0.7 (0.2) (164%) 0.02 0% (0.2) NM -1% (0.01) (0.00) NM 26.4
1996 E 41.4 182% 81% 29.9 72% 0.6 8% 0.4 0% 3.0 0.7 2.7 NM 0.0 0% 2.7 NM 6% 0.11 0.07 NM 24.4
1997
Q1 E 16.7 3% 148% 72% 11.3 67% 0.7 8% 0.1 -3% 0.6 0.5 0.2 (74%) 0.0 0% 0.2 (73%) 1% 0.01 0.01 -79% 26.5
Q2 E 17.1 2% 116% 72% 11.3 66% 0.7 8% 0.3 -2% 0.6 0.3 0.7 (53%) 0.0 0% 0.7 (52%) 4% 0.03 0.02 -56% 26.5
Q3 E 17.5 2% 68% 72% 11.4 65% 0.7 8% 0.6 -1% 0.6 0.3 0.9 102% 0.0 0% 0.9 102% 5% 0.03 0.02 96% 26.6
Q4 E 17.7 1% 9% 73% 11.5 65% 0.7 8% 0.7 0% 0.6 0.3 1.0 (604%) 0.0 0% 1.0 ##### 6% 0.04 0.02 -566% 26.6
1997 E 69.0 67% 72% 45.5 66% 2.7 4% 1.7 2% 2.5 1.3 2.9 8% 0.0 0% 2.9 9% 4% 0.11 0.07 -4% 26.6
1998
Q1 E 18.0 2% 8% 72% 11.5 64% 0.7 8% 0.8 1% 0.5 0.3 1.1 330% 0.0 0% 1.1 330% 6% 0.04 0.04 609% 26.8
Q2 E 18.5 2% 8% 73% 11.6 63% 0.7 8% 1.1 2% 0.6 0.3 1.4 99% 0.0 0% 1.4 99% 8% 0.05 0.05 228% 26.8
Q3 E 18.7 1% 7% 73% 11.6 62% 0.8 8% 1.3 3% 0.6 0.3 1.6 75% 0.0 0% 1.6 75% 9% 0.06 0.06 189% 26.8
Q4 E 19.0 1% 7% 73% 11.7 62% 0.8 8% 1.4 3% 0.6 0.3 1.7 66% 0.0 0% 1.7 66% 9% 0.06 0.06 175% 26.8
1998 E 74.2 8% 73% 46.5 63% 3.0 8% 4.5 2% 2.3 1.0 5.8 100% 0.0 0% 5.8 100% 8% 0.22 0.22 230% 26.8