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cefazolin

cefazolin

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Published by Conn_Casipe_8158

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Published by: Conn_Casipe_8158 on Jan 23, 2011
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04/09/2013

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Generic Name:
Cefazolin
Brand Name:
Ancef 
Dosage:
250 mg
CLASSIFICATIONS
Therapeutic:
Anti-infectives
Pharmacologic:
First generation cephalosphorins
ACTIONS
• Bind to bacterial cell wall membrane, causing cell death.• Active against many gram-positive cocci including: Streptococcuspneumoniae, Group A beta-hemolytic streptococci; Penicillinas-producingstaphylococci.
INDICATION
•Treatment of:
Skin & skin structure infections; pneumonia; urinary tract infections; bone & joint infections
CONTRA INDICATIONS
Contraindicated in:
•Hypersensitivity to cephalosphorins. Serious hypersensitivity to penicillin.
Use Cautiously in:
• Renal impair- ment• History of GI disease, especially colitis• Geriatric patients (consider age-related decrease in body mass,renal/hepatic/ cardiac function, concurrent medications and chronic diseasestates)• Pregnancy or Lactation
SIDE EFFECTS/ ADVERSE EFFECTS
• CNS:Seizures (high doses)• GI:Pseudomembranous colitis, diarrhea, nausea, vomiting, cramps• GU:Interstitial nephritis• DERM:Rashes, urticaria

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