Welcome to Scribd. Sign in or start your free trial to enjoy unlimited e-books, audiobooks & documents.Find out more
Download
Standard view
Full view
of .
Look up keyword
Like this
8Activity
0 of .
Results for:
No results containing your search query
P. 1
Cefazolin

Cefazolin

Ratings: (0)|Views: 573|Likes:
Published by Conn_Casipe_8158

More info:

Published by: Conn_Casipe_8158 on Jan 23, 2011
Copyright:Attribution Non-commercial

Availability:

Read on Scribd mobile: iPhone, iPad and Android.
download as DOC, PDF, TXT or read online from Scribd
See more
See less

02/05/2015

pdf

text

original

 
Cefazolin
Generic Name:
Cefazolin (sef-A-zoe-lin)
Brand Name:
Generic only. No brands available.cephalosporins
Possible side effects of Cefazolin :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:Loss of appetite; mild diarrhea; nausea; stomach cramps; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest;swelling of the mouth, face, lips, or tongue); bloody stools; decreased urination; fever;hoarseness; pain, swelling, or redness at the injection site; red, swollen, or blistered skin;seizures; severe diarrhea; severe nausea or vomiting; severe stomach pain/cramps; unusual bruising or bleeding; unusual tiredness; vaginal irritation or discharge; white spots in the mouth;yellowing of the eyes and skin.
Gastrointestinal:
 Diarrhea,oral candidiasis(oral thrush), vomiting,nausea, stomach cramps, anorexiaandpseudomembranous colitis. Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment (see
). Nausea and vomiting have been reportedrarely.
Allergic:
Hematologic:
 Neutropenia,leukopenia, thrombocytopenia,thrombocythemia.
Hepatic:
Transient rise in SGOT, SGPT, andalkaline phosphatase levels has been observed. As with other cephalosporins, reports of hepatitis have been received.
Renal:
As with other cephalosporins, reports of increased BUN and creatinine levels, as well as renalfailure, have been received.
Local Reactions:
Rare instances of  phlebitishave been reported at site of injection. Some induration has occurred.
Other Reactions:
Genital and anal pruritus (including vulvar pruritus, genital moniliasis, and vaginitis).
 
Indications:
Cefazolin for Injection USP and Dextrose Injection USP is indicated in the treatment of the followinginfections due to susceptible organisms:
Respiratory Tract Infections:
Due to
S. pneumoniae, S. aureus
(including beta-lactamase-producingstrains) and
S. pyogenes.
Injectable benzathinepenicillinis considered to be the drug of choice in treatment and prevention of streptococcal infections, including the prophylaxisof rheumatic fever . Cefazolin is effective in the eradication of streptococci from thenasopharynx;however, data establishing the efficacy of cefazolin in the subsequent prevention of rheumatic fever are not available.
Urinary Tract Infections:
Due to 
E. coli , P. mirabilis.
Skin And Skin Structure Infections:
Due to
S. aureus
(including beta-lactamase-producing strains),
S. pyogenes,
and other strains of streptococci.
Biliary Tract Infections:
Due to
E. coli,
various strains of streptococci,
P. mirabilis,
and
S. aureus.
Bone And Joint Infections:
Due to
S. aureus.
Genital Infections:
(i.e.,prostatitis,epididymitis) Due to
E. coli, P. mirabilis.
Septicemia:
Due to
S. pneumoniae, S. aureus
(including beta-lactamase-producing strains),
P. mirabilis,E. coli.
Endocarditis:
Due to
S. aureus
(including beta-lactamase-producing strains) and
S. pyogenes.
Appropriate culture and susceptibility studies should be performed to determine susceptibility of thecausative organism to cefazolin.
Perioperative Prophylaxis:
The prophylactic administration of cefazolin preoperatively, intraoperatively,and postoperatively may reduce the incidence of certain postoperative infections in patients undergoingsurgical procedures which are classified as contaminated or potentially contaminated (e.g., vaginalhysterectomy, and cholecystectomy in high-risk patients such as those older than 70 years, with acute cholecystitis, obstructive jaundice, or common duct bile stones).The perioperative use of cefazolin may also be effective in surgical patients in whom infection at theoperative site would present a serious risk (e.g., during open-heart surgery and prosthetic arthroplasty).The prophylactic administration of cefazolin should usually be discontinued within a 24-hour period after the surgical procedure. In surgery where the occurrence of infection may be particularly devastating (e.g.,open-heart surgery and prosthetic arthroplasty), the prophylactic administration of cefazolin may becontinued for 3 to 5 days following the completion of surgery.If there are signs of infection, specimens for cultures should be obtained for the identification of thecausative organism so that appropriate therapy may be instituted. (See
DOSAGE ANDADMINISTRATION.
)

Activity (8)

You've already reviewed this. Edit your review.
Musie added this note
Like the presentation
Musie liked this
1 thousand reads
1 hundred reads
nuccleus liked this
Diwata Custodio liked this
Merry Mee liked this

You're Reading a Free Preview

Download
scribd
/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->