Seropositivity to Herpes Simplex Virus Antibodiesand Risk of Alzheimers Disease: A Population-BasedCohort Study
PLoS ONE 2008; 3(11): e3637.doi:10.1371/journal.pone.0003637
Luc LetenneurINSERM U 897, Bordeaux, FranceLuc.email@example.com
no statistically significant difference in serumantibody titres to HSV in a sample of 33 Alzheimersdisease (AD) patients and 28 controls.
in a sample of 19 AD patients and 21 controls, theproportion of HSV-positive subjects was not differentbetween AD and control groups but increased titresof anti HSV antibodies observed in the control group.
he PAQUID study
Longitudinal cohort of 3 777 subjects aged 65years and older, living at home in South-westFrance.
Subjects were followed for 14 years with regularcognitive evaluations.