Basic Pharmacokinetics REV. 00.1.6
Copyright © 1996-2000 Michael C. Makoid All Rights Reservedhttp://pharmacy.creighton.edu/pha443/pdf/
2.1 Concepts of Mathematics
Pharmacokinetcs is a challenging field involving the application of mathematicalconcepts to real situations involving the absorbtion, distribution, metabolism andexcretion of drugs in the body. In order to be successful with pharmacokinetics, acertain amount of mathematical knowledge is essential.
This is just a review.Look it over. You shouldbe able to do all of thesemanipulations.
This chapter is meant to review the concepts in mathematics essential for under-standing kinetics. These concepts are generally taught in other mathematicalcourses from algebra through calculus. For this reason, this chapter is presented asa review rather than new material. For a more thorough discussion of any particu-lar concept, refer to a college algebra or calculus text.Included in this section are discussions of algebraic concepts, integration/differen-tiation, graphical analysis, linear regression, non-linear regression and the LaPlacetransform. Pk Solutions is the computer program used in this course.
Something new -LaPlace transforms.Useful tool.
A critical concept introduced in this chapter is the LaPlace transform. The LaPlacetransform is used to quickly solve (integrate) ordinary, linear differential equa-tions.
by Micromath Scientific Software, Inc.
is available for work-ing with the LaPlace transform for problems throughout the book.
1.MicroMath Scientific Software, Inc., P.O. Box 21550, Salt Lake City, UT 84121-0550,