Pathophysiology of Acute Gastroenteritis

Predisposing Factors Precipitating Factors

• Age • Contaminated
• Malnutrition food and water
Ingestion of fecally
contaminated food &
water

Direct invasion of the Endotoxins are

bowel wall released

Stimulation and
destruction of mucosal
lining of the bowel wall Attempted defecation
(Tenesmus)

Digestive & absorptive

malfunction

Excessive gas formation Increase peristaltic Secretion of F&E in the

movement intestinal lumen

GI Distention
Mild Diarrhea
(2-3 Stools)

Nausea & Vomiting

Fluids & Electrolytes
Imbalance

Increased protein in the

lumen

LI is overwhelmed &
unable to reabsorb the
lost fluid

Intense Diarrhea
(>10x) (Watery
Stool)

Serious Fluid Volume

Deficit

If untreated...
Hypovolemic Shock

Death