The most strange anomalies in medicine, all of them are rare diseases with bizarresigns and symptoms. Some of them have already been described in MedTempus. Iindicate so with links. They are ordered from greater to smaller frequency.
10-Congenital insensitivity to pain
: 100 documented cases in U.S.A. Thefrequency in other countries is unknown and it isusually undiagnosed.
: Recently discovered. It is caused by amutation in a gene implicated in the synthesis of atype of sodium channel which is mainly located inneurons associated with the reception andtransmission of pain stimulus.
: They are totally normal people in the sense of touch and in thesensibility of cool, heat, pressure and tickling. However, with a normal act wich would cause pain (as to nail a needle) it does not cause them any painful sensation. As a result of this, they usually die younger by traumatism and several injuries because of their lack of pain perception. They must be under supervision in early agesso that they can´t injure themselves.
: Around 80 documented cases in Spain, 200 inU.K… In Europe, around 300 kids appear with this syndromeeach year.
: Unknown. Nobody knows if those that are affected inthe origine of the disesase are nerves, brain stem or muscles.Many and varied hypothesis but without proofs that confirmthem.
:Because some face nerves are not developed, thepeople who are born with this syndrome lack face expression.They cannot smile, frown, move the eyes laterally or control the blinking. They are often found sleeping with the open eyes. They have greatdifficulties in sucking, swallowing, speaking and any activity in which are impliedmuscles of the face.
: Around 500 documented cases in the world. The real frequency in thepopulation is not known.
: Hermaphrodites are chimeras. It is caused by the fusion of two zygotes of differente sex. That is to say, a first spermatozoid would fertilize a ovum and, later,another spermatozoid would fertilize another ovum. The zygotes that would beformed and that were destined to being twins, end up fusing and becoming an only