is a ubiquitous soil borne pathogen responsible for Crown Gall disease (right), affecting many higher species of plant. The pathogen is a problem for agriculture all over the world. DNA transfer from
to eukaryotic cells is the only known example of inter-kingdom DNAtransfer (Dumas
, (2001). It is therefore unsuprising that
has evolvedits own unique and specialised system to accomplish this task, which is of great interestto plant scientists. The information contained in this website will explore the history andall that we know about this remarkable micro-organism.This website aims to give an insight into the bacterium,with information about the research that has been carried out inthe past, and how the knowledge we have gained can be appliedto help alleviate problems facing food production around theworld. Other potential uses of the technology are also reviewed,such as using our knowledge of
to produce a biocontrol agent and producing effective transformation vectorssuch as the pGreen binary vector. This website also includes acomprehensive list of references for anyone wishing to readfurther into any aspect of the research surrounding the bacterium.The study of transgenic or genetically modified plants is currently attractingsignificant interest because of its potential applications in industry, the environment, inthe home and in medicine. Most genetic modification is perceived as being the insertionof foreign DNA into the genome of the target organism, and hence there is much debateas to whether this will have any unseen consequences in the future, and whether it ismorally acceptable. There are also many problems associated with current methods of transgenic plant production, most notably the low transformation frequency encountered,or the failure of transgenic plants to grow at all. The use of
intransgenic plant production has arisen from the need to find an effective vector system tosuccessfully integrate the gene of interest into the correct area of the plant genome.In recent years, the subject of uncontrolled cellular growth;
, has been thefocus of considerable attention as a result of its life threatening nature in humans.Extensive studies have unlocked information and provided a comprehensive knowledge base of undifferentaiated tissue growth in mammals, however little attention has been paid to cancer found in the plant kingdom.
causes one of themost common plant tumours, commonly known as Crown Gall disease which affects awide variety of plants. Much research has taken place in an effort to understand themechanism by which the bacterium infects the plant cell, in the hope that the bacterium