However, most of these cases will not develop the full-blown disease;asymptomatic, latent infection ismost common. About one in ten of these latent infections will eventually progress toactive disease, which, if left untreated, kills more than half of its victims. In 2004,mortality and morbidity statistics included 14.6 million chronic active cases, 8.9 millionnew cases, and 1.6 million deaths, mostly indeveloping countries.
When the disease becomes active, 75% of the cases are pulmonaryTB. Symptomsinclude chest pain,coughing up blood, and a productive, prolonged cough for more thanthree weeks. Systemic symptoms include fever, chills,night sweats,appetite loss, weightloss, pallor, and often a tendency to fatigue very easily.