Vary in presentation according to site of infection
High living standards= Lowered incidence of T. capitis= Increased incidence of T.Pedis (athletes foot. Shoes & stockings -> warmth & moisture)
Increased Dermatomycosis due to Trichophyton rubrum (an anthropophilic dermatophytethe most common dermatophyte pathogen worldwide)
Transmission of zoophilic dermatophytesDirect contactFomites
Geophilic dermatophytesFarmersGreenhouse workers
The most common of the 3 anthropophilic dermatophytes
HOST FACTORS which favour diseaseAbraded skinOcclusive clothing, footwear, dressingsPresence of other cutaneous diseases like atopic dermatitisDermatophyte invade keratinized layer of skin -> produce keratinases that digest keratinMost lesions contained within this anatomic boundaryMay be self-limitingWidespread infection seen in patients:-
On immunosuppressive drug regimes-
Have endocrinopathies like Cushings disease
Superficial Mycosis II
Pathogenic features refer diagrama.
Normal continual shedding of stratum corneum protects from dermatophytesb.
Inflammatory reactions following dermatophytoses1.
Penetration of stratum corneum CMI response2.
Vesiculation occurs in severe cases3.
Stratum corneum contains nucleated cells!-
Inflammatory reaction increases epidermal cell division rates pass more rapidlythrough epidermis-
Full differentiation of cells of different strate does not take place