: Response by neutrophils, leading to neutrophilia (increase in neutrophils)engulf and kill bacteria, failure results in infection.
: Response by lymphocytes, make immunoglobulins and memory cells, vaccinationresults in production of memory cells.
ABNORMAL WHITE BLOOD CELLS
When something goes wrong with WBC production, result is Congenital or acquiredimmunodeficiency, very serious condition, often fatal, treated with bone marrow transplant or genetherapy. Examples shown below.
Proliferation of primitive precursor cells usually only found in bone marrow
Proliferation without differentiation
Replaces normal bone marrow cells, leads to: anaemia: palor and lethargyneutropenia: infectionthrombocytopenia: bleedingAcute leukaemia can lead onto
Acute myeloblastic leukaemia,
this is where Malignant proliferationof the precursor myeloblasts in the bone marrow occurs.Immunological memory.Vital to immunity!3 types:Generate antibodies.Aid B-cells inAntibodygeneration.Produceimmunoglobulins,when stimulatedby a foreignantigen.NaturalKillercellsDifferentiate intoplasma cellsNamed afterBone marrow.B-LymphocytesT-lymphocytesSome arehelper cells.Named afterThymus.Some arecytotoxic.Memory cells.