CENTRAL NERVOUS SYSTEM
Brain and Spinal Cord.
[Spinal cord terminates at L
therefore a LUMBAR TAP is performed at L
no risk for spinal cord damage]
I. CELLSA. NEURONS
Basic cells for nerve impulse and conduction.
ability of neuron to be affected by changes in external environment.
ability of neuron to transmit a wave of excitation from one cell to another.
once destroyed not capable of regeneration.
TYPES OF CELLS BASED ON REGENERATIVE CAPACITY1. Labile
Capable of regeneration.Epidermal cells, GIT cells, GUT cells, cells of lungs.
Capable of regeneration with limited time, survival period.Kidney cells, Liver cells, salivary cells, pancreas.
Not capable of regeneration.Myocardial cells, Neurons, Bone cells, Osteocytes, Retinal Cells.
Support and protection of neurons.
blood brain barrier
Majority of brain tumors (90%) arises from called
in CNS. Act as insulator and facilitates rapid nerve impulse transmission
3. Microglia4. EpindymalSUBSTANCES THAT CAN PASS THE BLOOD-BRAIN BARRIER1. Ammonia
Hepatic Encephalopathy (Liver Cirrhosis)
Early Signs of Hepatic Encephalopathy
(flapping hand tremors).
Late Signs of Hepatic Encephalopathy
(ammonia like breath)
Decrease LOC [hepatic coma][AIRWAY FOR HEPATIC COMA]
2. Carbon Monoxide and Lead Poisoning
Can lead to
.[PILL ROLLING TREMORS]
For Lead poisoning
Hyperbaric oxygenation (100% O
For carbon monoxide poisoning