Welcome to Scribd, the world's digital library. Read, publish, and share books and documents. See more ➡
Download
Standard view
Full view
of .
Add note
Save to My Library
Sync to mobile
Look up keyword
Like this
28Activity
×
0 of .
Results for:
No results containing your search query
P. 1
Multiple Choice Questions in Molecular Biology

Multiple Choice Questions in Molecular Biology

Ratings: (0)|Views: 7,447|Likes:
Published by danishuddin_danish

More info:

Published by: danishuddin_danish on Jun 06, 2011
Copyright:Attribution Non-commercial

Availability:

Read on Scribd mobile: iPhone, iPad and Android.
download as PDF, TXT or read online from Scribd
See More
See less

06/20/2013

pdf

text

original

 
 
MultipleChoiceQuestionsInMolecularBiology
 
 
2
 EukaryoticGeneExpression
 
3
Problem 1: Post transcriptional modification to the 3'-end of eukaryoticmRNAs
What is added to the 3'-end of many eukaryotic mRNAs after transcription?
A.
B.
C.
D.
E.
 
Transcription of eukaryotic protein-coding genes
 
Transcription of eukaryotic protein-coding genes results in an mRNA precursor molecule thatis extensively processed in the cell nucleus.When eukaryotic nuclear genes for proteins are transcribed by RNA polymerase, the productis a precursor RNA (pre-mRNA) that is further processed in the nucleus before transport tothe cytoplasm for translation. The important processing steps are the following:1.
Capping
. A modified G-nucleotide, termed a "cap," is added to the 5'-end of most mRNA.The cap is retained in mRNA and functions in ribosome binding and mRNA stability.2.
3'-Polyadenylation
. A tail of A-nucleotides, generally 100-200 long, is added to the 3'-endof most eukaryotic pre-mRNAs. The poly A tail, which is not coded in the DNA, is alsoretained in the mRNA exported to the cytoplasm.3.
Intron Splicing
. The pre-mRNA transcripts often contain introns, which are noncodingsequences that interrupt the coding regions known as exons. Introns are removed and exonsare joined together by the spliceosome in the nucleus.
B.
a poly A tailA tail of A-nucleotides, generally 100-200 long, is added to the 3'-end of most eukaryotic pre-mRNAs. The poly A tail, which is not coded in the DNA, is also retained in the mRNAexported to the cytoplasm.

Activity (28)

You've already reviewed this. Edit your review.
1 hundred reads
1 thousand reads
Brittney Brown liked this
Tony Ike Roberts liked this
Suneeta Sharma liked this
Carly Rain Adams liked this
John Mayan liked this
Alexandria Slack liked this
Erik Bonilla liked this

You're Reading a Free Preview

Download
/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->