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Addressing Race and Genetics

Addressing Race and Genetics

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Michael J. Rugnetta and Khusboo Desai examine issues regarding racial and ethnic health disparities that need to be addressed in order for personalized medicine to offer the greatest benefit to all.
Michael J. Rugnetta and Khusboo Desai examine issues regarding racial and ethnic health disparities that need to be addressed in order for personalized medicine to offer the greatest benefit to all.

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Categories:Types, Research, Science
Published by: Center for American Progress on Jun 13, 2011
Copyright:Attribution Non-commercial

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01/02/2013

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Addressing Race and Genetics
Health Disparities in the Age o Personalized Medicine
Michael J. Rugnetta and Khusboo Desai March 2011
www.SCIENCEprogrESS.org
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Addressing Race and Genetics
Health Disparities in the Age o Personalized Medicine
Michael J. Rugnetta and Khusboo Desai March 2011
 
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Science Progress • www.scienceprogress.org |
 aressng Re n Genes
Introduction and summary
Te human genome sequence has been ully compleed or a decade now and he priceo ull genome sequencing is dropping precipiously. Many believe ha wih hese devel-opmens, a new era o personalized medicine is abou o hi ull speed. Personalizedmedicine is essenially “he use o geneic suscepibiliy or pharmacogeneic esing oailor an individual’s prevenive care or drug herapy,” alhough some deniions alsoinclude he developmen o paien oucomes research, healh inormaion echnology,and care delivery models.
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Pu more simply, i means he developmen o medicines andherapies ailored o paiens’ unique geneic rais and risks.Te eld is evolving rapidly bu many hurdles sill remain. Individually ailored drugs based on a paien’s geneic makeup are ar o, and he cos o developing drugs orgeneic subpopulaions wih largely similar geneic rais or one or more diseaseshinders developmens in his arena. Similarly, he lack o sandards surrounding direc-o-consumer geneic ess and he lack o robus, large-scale genomic daa or many diseases and condiions are addiional hurdles.Neverheless, personalized medicine is making is way ino he mainsream. Esimaes by PricewaerhouseCoopers indicae ha he marke or personalized medicine, currenly a$232 billion indusry, will grow a a rae o 11 percen annually.
2
Personalized medicineis also making serious srides in he pharmaceuical indusry wih drugs like he coloncancer drug Erbiux, which is mos eecive in paiens wih a cerain geneic muaion.Personalized medicine also has he poenial o rein in rising healh care coss. Forinsance, physicians can beter preven adverse drug reacions by using geneic inorma-ion o calibrae he ideal dosage o he blood-hinning drug Wararin or an individualpaien. Tis alone could preven 85,000 serious bleeding cases and 17,000 srokes, andsave he healh care sysem $1.1 billion annually.
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Bu he healh care and scienic communiies will sill have o answer imporan ques-ions abou who will have access o hese new medical advancemens as hey develop.Healh dispariies persis beween dieren groups or various reasons including accesso care, liesyle acors, socioeconomic saus, and geneics. Sudies indicae ha minor-iies have less access o healh care and generally receive a lower qualiy o care. Sudiesshow ha Arican Americans have lower incidence o breas cancer han whie women,or example, bu suer greaer moraliy.
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Hear disease is widespread among minoriiesand a leading killer in he Arican-American communiy.

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