is defined as the process of enclosing micron sized particles of solidsor droplets of liquids or gasses in an inert shell, which in turn isolates and protects themfrom the external environment.Particle size below 1µm-nanoparticles, nanocapsules, nanospheresParticles diameter between 3 -800µm-micro particles or microcapsules or microspheres.Particles larger than 1000µm -macro particles.Micro particles or microcapsules consist of two components:Core materialCoating materialAdvantages:
to protect the sensitive substances from the external environment.
to mask the organoleptic properties like colour, taste, odour of the substance.
to obtain controlled release of the drug substance.
for safe handling of the toxic materials.
to get targeted release of the drug.
to avoid adverse effects like gastric irritation of the drug e.g. aspirin is the first drugwhich is used to avoid gastric irritation.
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