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Featured Product of Selleck---AG14361(Purity>99%)

Featured Product of Selleck---AG14361(Purity>99%)

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Published by Selleck Chem
Technical Data:
M.Wt: 320.39
Formula: C19H20N4O
Solubility: Unknown
Purity: >99%
Storage: at -20℃ 2 years
CAS No.: 328543-09-5
Biological Activity of AG14361:

AG14361 is a potent poly(ADP-ribose) polymerase (PARP-1) inhibitor with a GI50 of 10.9 µM. It caused a >3-fold sensitization of PARP-1+/+ cells to topotecan compared with a References on AG14361:

[1] Calabrese CR et al. J Natl Cancer Inst. 2004 Jan 7;96(1):56-67.

[2] Smith LM et al. Clin Cancer Res. 2005 Dec 1;11(23):8449-57.

[3] Curtin NJ et al. Clin Cancer Res. 2004 Feb 1;10(3):881-9.
Technical Data:
M.Wt: 320.39
Formula: C19H20N4O
Solubility: Unknown
Purity: >99%
Storage: at -20℃ 2 years
CAS No.: 328543-09-5
Biological Activity of AG14361:

AG14361 is a potent poly(ADP-ribose) polymerase (PARP-1) inhibitor with a GI50 of 10.9 µM. It caused a >3-fold sensitization of PARP-1+/+ cells to topotecan compared with a References on AG14361:

[1] Calabrese CR et al. J Natl Cancer Inst. 2004 Jan 7;96(1):56-67.

[2] Smith LM et al. Clin Cancer Res. 2005 Dec 1;11(23):8449-57.

[3] Curtin NJ et al. Clin Cancer Res. 2004 Feb 1;10(3):881-9.

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Categories:Types, Research, Science
Published by: Selleck Chem on Jun 28, 2011
Copyright:Attribution Non-commercial

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