Notes: vomiting/diarrhoea are associated with avid Na + retention; hence urine Na+ will be low.SIADH: diagnosis requires normal renal, adrenal and thyroid function. Patient must be euvolaemic. Diuretic therapy must be excluded.Investigations: Serum U&Es including Mg
can provoke ADH release), TFTs and serum osmolality. Urinary U&Es and urine osmolality.Cautions with treatment: over-rapid correction of hyponatraemia can lead to central pontine myelinosis.