destruct, goes awry and results in cell proliferation a process called as
As BPH progresses, overgrowth occurs in the central area of theprostate called the transition zone, which wraps around the urethra (the tubethat carries urine through the penis). This pressure on the urethra can causelower urinary symptoms that have been the basis for diagnosing BPH. Itshould be noted that BPH is not always the cause of these symptoms. Anenlarged prostate may be accompanied by few symptoms, while severe LUTSmay be present with normal or even small prostates and are most likely dueto other conditions. Symptoms of BPH may include;
Difficulty in starting to passurine (hesitancy), a weak stream of urine, dribbling after urinating, the need to strain to passurine, incomplete emptying of bladder, difficulty to control the urination urge, having to get upseveral times in the night to pass urine, feeling a burning sensation when passing urine.Sometimes a man is unaware of an obstruction until he suddenly cannot urinate at all.This condition is called acute urinary retention. It is a dangerous complication that can damagethe kidneys and may require emergency surgery. In general, BPH progresses very slowly andacute urinary retention is very uncommon. Men with BPH at highest risk for this complicationtend to be elderly and to have moderate to severe lower voiding symptoms. Taking anti-hypertensive drugs (except for diuretics) or antiarrhythmic drugs may also increase the risk.Bladder obstruction can also cause bladder stones, blood in the urine, urinary tract infection, andincontinence. Unfortunately, no current tests can accurately predict which men are at higher risk for complications, although men with a weak urine stream and larger prostates are at higher risk for urinary retention.Diagnostic tests used to confirm Benign Prostatic Hyperplasia include Digital RectalExam,
Urinalysis, Serum Creatinine, Postvoid Residual Urine, Ultrasound, Urethrocystoscopy.