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Table Of Contents

1 INTRODUCTION
2 EPIDEMIOLOGY
2.1 Overview
2.2 Basal cell carcinoma
2.2.1 Incidence in the general population
2.2.2 Environmental risk factors
2.2.3 Genetic epidemiology
2.3 Squamous cell carcinoma and related keratinocyte tumours
2.3.1 Incidence in the general population
2.3.2 Environmental risk factors
2.3.3 Human papilloma virus
2.3.4 Genetic epidemiology
2.3.5 Tobacco and skin cancer
3.2.4 Morphoeic
3.3 Squamous cell carcinoma and related keratinocyte tumours
3.3.1 Squamous cell carcinoma
3.3.2 Solar keratoses (including Bowenoid keratosis)
3.3.3 Squamous cell carcinoma in-situ (Bowen’s disease)
4 PATHOLOGY (INCLUDING BIOPSY)
4.1 Basal cell carcinoma
4.3 Keratoacanthoma
4.4 Biopsy considerations and the biopsy report
4.4.1 Communication between the clinician and the pathologist
4.4.2 Clinical information recommended to be provided on request form
5 PROGNOSIS
5.1 Basal cell carcinoma
5.1.1 Introduction
5.2 Squamous cell carcinoma
5.2.1 Introduction
6 SURGICAL TREATMENT
6.1 Introduction
6.2 Objectives of treatment
6.3 Principles of surgical management
6.4 Advantages and disadvantages
6.5 Basal cell carcinoma
6.5.1 Tumour size and site
6.5.2 Tumour type
6.5.3 Perineural invasion
6.5.4 Incompletely resected BCC
6.5.5 Recurrent basal cell carcinoma
6.6 Squamous cell carcinoma
6.6.1 Tumour size
6.6.2 Anatomic site
6.6.3 Histological features
6.6.4 Rapidly growing tumours
6.6.5 Previously treated SCC
6.6.6 Immunosuppressed patients
6.6.7 Aetiology
6.7 Metastatic disease
6.7.1 Basal cell carcinoma
6.7.2 Squamous cell carcinoma
6.8 Mohs micrographically controlled surgery
6.9 Anticoagulants and surgery
7 RADIOTHERAPY
7.1 Introduction
7.1.1 Tissue conservation
7.2 Side effects of radiotherapy
7.2.1 Acute radiation effects
7.2.2 Late radiation effects
7.2.3 Relative indications for definitive radiotherapy
7.2.4 Relative contraindications for definitive radiotherapy
Relative contraindications for definitive radiotherapy are:
7.3 Basal cell carcinoma
7.3.2 Residual basal cell carcinoma following radiotherapy
7.3.3 Post-operative radiotherapy for residual BCC following surgery
7.3.4 Recurrent basal cell carcinoma following radiotherapy
7.4 Primary cutaneous squamous cell carcinoma
7.4.1 Definitive treatment of primary cutaneous SCC
7.4.2 Post-operative radiotherapy of primary cutaneous SCC
7.5 Regional (nodal) metastatic disease (non-distant)
7.5.1 Basal cell carcinoma
7.5.2 Squamous cell carcinoma
7.6 Solar keratosis and SCC in situ
7.7 Keratoacanthoma
8 CRYOTHERAPY, CURETTAGE AND DIATHERMY/ELECTRODESICCATION
8.1 Introduction
8.1.1 Advantages
8.1.2 Disadvantages
8.2 Cryotherapy
8.2.1 Basal cell carcinoma
8.2.2 Squamous cell carcinoma and related lesions
8.3 Curettage and diathermy/electrodesiccation
8.3.1 Mechanism
8.3.2 Basal cell carcinoma
8.3.3 Control rates for BCC treated by serial curettage by diameter77,79,80
Table 8.1 Control rates for BCC treated by serial curettage by diameter
8.3.4 Squamous cell carcinoma and related lesions
9.1 Interferon
9.1.1 Introduction
9.1.2 Basal cell carcinoma and squamous cell carcinoma
9.2 Imiquimod 5% cream*
9.2.1 Solar keratoses
9.2.2 Superficial basal cell carcinoma
9.2.3 Nodular basal cell carcinoma
9.2.4 Squamous cell carcinoma in situ (Bowen’s disease)
9.3 3% Diclofenac gel
9.4 5% 5-fluorouracil cream
9.5 Photodynamic therapy*
9.5.1 Introduction
9.5.2 Solar keratoses
9.5.3 Squamous cell carcinoma in situ (Bowen’s disease)
9.5.4 Squamous cell carcinoma
9.5.5 Superficial basal cell carcinoma
9.5.6 Nodular cell basal cell carcinoma
9.5.7 Long term results for PDT
9.6 Follow up
9.7 Laser therapy
10.5 Chronic lymphocytic leukaemia patients
10.6 HIV patients
10.7 Rheumatoid arthritis patients
10.8 Management of transplant patients
10.9 Specific treatments
10.9.1 Photodynamic therapy
10.9.2 5-Fluorouracil
10.9.3 Imiquimod
10.9.4 Radiotherapy
10.10 Recurrent aggressive SCC
10.11 Prevention
11 PREVENTION (INCLUDING CHEMOPREVENTION)
11.1 Introduction
11.2 Chemoprevention
11.2.1 Synthetic retinoids
11.3 Vitamin D
12 METASTASIS FROM NON-MELANOMA SKIN CANCER
12.1 Basal cell carcinoma
12.1.1 Distant metastases
12.1.2 Chemotherapy
12.2 Squamous cell carcinoma
12.2.1 Distant metastases
12.2.2 Chemotherapy
13.2 Squamous cell carcinoma
14 WHO TREATS AND PROBLEMS TO REFER
14.1 Introduction
14.2 Whether to treat or refer
14.3 Problem areas requiring experience and care
14.4 Problems to refer
14.5 Follow-up
14.6 Opportunistic screening
14.7 Education of GPs
14.8 Education of the patient
14.9 Summary
15 ECONOMICS OF BASAL CELL AND SQUAMOUS CELL CARCINOMA AND RELATED CONDITIONS
15.1 The growing economic burden in Australia
15.2 Medicare Australia costs per lesion and per individual
15.3 Patient out-of-pocket expenses
15.5 Investment in skin cancer prevention
16 QUESTIONS AND CONCERNS THAT MAY ARISE DURING CONSULTATION
16.1 Specific topics
16.1.1 Susceptibility
16.1.2 Prevention
16.1.3 Diagnostic pointers
16.1.4 Consulting
16.1.5 Treatment
16.1.6 Progress/watchfulness
16.2 In general
APPENDIX 2 SOURCES FOR CANCER INFORMATION
APPENDIX 4 GUIDE DEVELOPMENT PROCESS
ABBREVIATIONS
GLOSSARY
INDEX
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Basal Cell Carcinoma Squamous Cell Carcinoma Guide Nov 2008-Final With Corrigendums

Basal Cell Carcinoma Squamous Cell Carcinoma Guide Nov 2008-Final With Corrigendums

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Published by: Boofy27 on Aug 10, 2011
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