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NURS 2516 Clinical Medications Worksheets

(You will need to make additional copies of these forms)

Generic Name TradeName Classification Dose Route Time/frequency


diphenhydramine Benadryl allergy, cold, and 12.5 mg IVP Q 6 hr.PRN
cough remedies,
antihistamines ,
antitussives
Peak Onset Duration For IV meds, compatibility with IV drips and /or solutions
unknown rapid 4-8 hr Direct IV: May be further diluted in 0.9% NaCl, 0.45% NaCl,
D5W, D10W, D5/0.9% NaCl, D5/0.45% NaCl, D5/0.25% NaCl,
Ringer's solution, LR, and dextrose/Ringer's combinations Rate:
Inject 25 mg over at least 1 min Y-Site Incompatibility:
♦allopurinol ♦amphotericin B cholesteryl sulfate ♦ cefepime
♦foscarnet
Mechanism of action and indications Nursing Implications (what to focus on)
(Why med ordered) Contraindications/warnings/interactions Hypersensitivity,
rolling of jaw May cause paradoxical excitation in young children
Significant CNS depressant and anticholinergic properties
Common side effects
CNS: drowsiness, dizziness, headache, paradoxical excitation
(increased in children),
EENT: blurred vision, tinnitus,
CV: hypotension, palpitations,
GI: anorexia, dry mouth, constipation, nausea,
GU: dysuria, frequency, urinary retention,
Derm: photosensitivity,
Resp: chest tightness,, thickened bronchial secretions, ,
wheezing,
Local: pain at IM site,
Interactions with other patient drugs, OTC or herbal Lab value alterations caused by medicine
medicines (ask patient specifically) Diphenhydramine may decrease skin response to allergy tests.
↑ risk of CNS depression with other antihistamines , alcohol , Discontinue 4 days before skin testing
opioid analgesics , and sedative/hypnotics Be sure to teach the patient the following about this
medication Caution patient not to use oral OTC
diphenhydramine products with any other product containing
diphenhydramine, including products used topically Pedi: Can
cause excitation in children. Caution parents or caregivers about
proper dose calculation; overdosage, especially in infants and
children, can cause hallucinations, seizures or death Inform
patient that this drug may cause dry mouth. Frequent oral
rinses, good oral hygiene, and sugarless gum or candy may
minimize this effect. Notify dentist if dry mouth persists for more
than 2 wk
Nursing Process- Assessment Assessment Evaluation
(Pre-administration assessment) Monitor carefully, Why would you hold or not give this Check after giving
assess for confusion, delirium, other anticholinergic med? Decreased dyskinesia in
side effects and fall risk. Institute measures to sedation and confusion due to increased parkinsonism and extrapyramidal
prevent falls. Assess movement disorder before and sensitivity to anticholinergic effects. reactions
after administration Monitor carefully, assess for confusion,
delirium, other anticholinergic side
effects and fall risk. Institute measures to
prevent falls

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