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INDEX NURS 2236 Clinical Form 3: Clinical Medications Worksheet

(You will need to made additional copies of these forms)


Generic Trade Classification Dose Route Time/Frequency
Name Name
quetiapine seroquel antipsychotic 100 mg PO Q HS

Peak Onset Duration Normal Dosage range


unknown unknown 8-12 hours Max- 800 mg per day

Why is your patient taking this medication? For IV meds, compatability with IV drips and/or solutions
psychotic disorder

Mechanism of action and indications Nursing Implications (what to focus on) use cautously in: Cardiovascular
Functions as an antagonist at multiple neurotransmitter Contraindications/warnings/interactions disease, cerebrovascular disease
receptors in the brain including 5HT, dopamine and dehydration or hypovolemia, History of seizures, Alzheimer's dementia, Hepatic
adrenergic alpha 1&2 receptors impairment, Hypothyroidism, history of suicide attempt

Decrease manifestation of psychoses or acute mania Contra- Hypersensitivity


Common side effects EPS, pseudoparkinsonism, akathisia, dystonia, tardive
dyskinesia, drowsiness, insomnia, agitation, anxiety, headache, seizures,
neuroleptic malignant syndrome, dizziness orthostatic hypotension, tachycardia
nausea, anorexia, constipation, abdominal pain, dry mouth, rash, asthenia
back pain, fever, ear pain, rhinitis,
Interactions with other patient drugs, OTC, or herbal Lab value alterations caused by medicine
medicines (ask patient specifically) cause increase in AST and ALT, may also cause anemia, thrombocytopenia,
antihistamines, opoid analgesics, sedative/hypnotics leukocytosis, leukopenia, may cause increase total cholesterol and triglycerides
Antihypertensives, phenytoin, thioridaxine, carbamazepine,
barbiturates, rifampin, corticosteriods, ketoconazole, Be sure to teach the patient the following about this medication
intraconazole, flluconazole, erthromycin instruct patient to take meds as directed, inform patient of EPS, advise patient to
change positions slowly, may cause drowsiness- caution patient to avoid driving
advise patient to avoid extremes in temperature- impairs body temperature
regulation, caution patient to avoid concurrent us of alcohol and other CNS
depressants, notify health care providor of sore throat, fever, or unusual bleeding
Nursing Process - Assessment Assessment Evaluation
(Pre-administration assessment Why would you hold or not give Check after giving
Monitor mental status, Monitor mood changes, this med? Evalution the patient for decrease In excited,
Assess for suicidal tendencies, Monitor Blood seizures manic, paranoic or withdrawn behavior, make
pressure and pulse before administraion, sure patient has swallowed medication and is
Observe patient carefully when administering to not cheeking or hording meds.
ensure medication is swallowed, Monitor for onset
of EPSMonitor for development of neuroleptic malignant syndrome

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