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Question bank - 5th sem

Question bank - 5th sem

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Published by Malavika Nadig

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Published by: Malavika Nadig on Aug 15, 2011
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01/16/2013

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~;o-:
~."
VisvesvarayaTechnological
Univergty
'B..E.Blctechnolngy-VSemester.
Il'ffMUNOLOG\,r
"CQDI::BY54
___
'
Max
Marks:100
'Time:
3Hours.
ModelQuestionPaper
.IRUCTIO~S:,
.Az""!C
any
five
fu
IIquestions,'iil
All
fullQuelitignscarryequalmarks.
)~JIM
account
ofbarriersto
classicalcpm:;'~ente.h.way1:..'-/"/';omarks
...aplain
jnnate
iinmuni~',.
E.'_'..--'.._.
=..,.~..--'..----
'5
marks
c...
lK
iU
ashort
noteonThymusgland.>",,.5marks
._yQrat,
fieImmunoglobulins?Give.schematicrepresentetionof'Jg'G'10marksb.'Writea
short
note
'on''
ijJa
d3"1'e~.',/.
5marks'
,HU'
A
A'"
\.;?
5marks'....0
III;'.'/
7,
,"pj6scrlbeindetail-themechanismofactionofCytotoxicTcellv':Iomaks.
.~te
a
shortnoteonT
cell
recep~'Oj:S.:/.....'.,·5
marks
Sr
''kite
a
shortnoteonopsonisaion.>.5marks
aDescribeindetailimmunoinvasivemechanismoftumors.
k~/
10marksb,ExplainhostVs
Graft
reaction..
,'10
marksa.
What
is
autoimmunity?Writeanaccountof
any
twoautoimmunedisorders
.in
hwnans.,·,·.'.'./-
lOtuitrksb.Explainthe
Immunological
aspectsofAIDS..
x>"
lO,ma_rk~.
",.a3ive
an
accountontypesofconventionalvaccines.Discuss'their
advantages
anddisadvantages...,,10marksb.Writeshortnotesen-
_,~lil,anized
'ant~bodies..
'~ymes(caalyticantibodies)...~5x2-10marks"""".aDiscussthemethodologyof
production
of
high
titre
polyclonal
antibodies._
;X
,,,.10marks
..5
marks
~Q~ethe'principleof~,'.',.....
'''':5
mBrlts
8).~plain,theprincipleand
any
two
types
ofenzyme
linked
immunosorbant
assHyS./',",-
10
marks
b.
Write.anoteon"",'.
i)
Irurn
uuoelectronruicroscopy.
~peket.immuno
electroph~resis/~
)
,
,
'5luarks5
marks
/.
 
Fifth
Semester
B.E.DegreeExamination,Dec
081
Jan09
Immunotechnology
Max.Marks:100
-
-
Note:
Answer
anyFIV~
fullquestions,selectingatleastTWO
from
eachpart.
-
PART~A-~tite
thedistinguishingfe~turesofinnateandadaptiveimmunity.\.'-~how
thecellsandorgansare
necessary
forimmuneresponse,
...EXplain
thestructure
of-various
classesofImmuneglobilins....Writetheconcisenoteon:i)Production
of
monoclonalantibodies
~
(10Marks)(10Marks)-
(to
Marks)
--i~-ceU
(10Marks)
a.-
BricOy
explainthestepsinvolvedinth~mechanismofT-cellactivation.ILWrite
the
explanatorynoteso~:~p~sentingc~.lls_ii)
~c
complex.
~F.xpIain
tbe
generalpropertiesandfunctionsofcytokines.~'bethe~~loustypesofhypersensitivity..
(10Marks)(10Marks),(1:0Marks)(10Marks)
_PART..:..B
._.EXPlain_the
treatmentandexperimental-therapeutic
approach"for
autoimmunediseases,
f\
---.(10Marks)'~"
II:.
Write
anoteon:i)
Rheumatoid
arthritis.ii).Mechanism
ofAIDS.(lOMarks)
---;r--
a.
DesCn~
thevarious
stepsinvolved
inmechanismofgraft
rejection.,~,_,.".'._.
(10
r,1~rks).
-"::---EXphiin'die
methodsinvolvedin.the
tissue-typing
for
the"detectionofHl.Auntigens.-.
.
'
..
.
.~~~
c..
Writeanyfourimmunosuppressivedrugs.
(02Marks)
...Ddioetbe
termvaccine,
Explain
thevarious'typesofvaccines'withhe"Ip
-of
suitable
cxa~pk:s-.
(10Marks)
C.
Explain
thegeneralcharacteristicsandapplicationsofstemcellsto
immunology.(08
Marks)
tr'
,'hat
arecatalyticantibodies?-.'.
(1)2Marks)
~ritc
the
principle
andapplicationsof.Radio
Immuno
Assaytechnique.
'_-WJilcanoteonfollowingwithrespecttoimmunodiagnosis.
VUOWlO
electrophoresisi~sternblotanalysisiii)~nofluorescence_"
..(12Marks)
(08Marks)
G
*****
 
Fifth
SemesterB.EDegreeExamination,Dec.07
I
.Jan,08
Immunology
s.;.
Max.Marks
Note:
AI,s....er
any
FWEflll/
questions.
hatisacquiredimmunity?Withsuitableexample,explain
different
typesof
ac
ununity,.-.(lOr
efineanantigen.Writeanaccountonqualitiesthatdetermineantige~,icitY:-Qi
(lOr
.
.~-'
..
.,r
escribethemechanismofmaturationandactivationofBvlymphocyte.ithillustration,explain
the'
typicalstructureofanantibody,.
.
.
~
.,
.(10
r
(1011
ritean
account
onantigenpresentingcells..Addanoteonmechanismof
phagocyte
(10
(plain
the
processofa-ctivationof
CD4
+
and
CDg
+
Tcells.(tohatishypersensitivity?Writeanaccountondelayedtypehypersensitivity,
(10
l'
tplaintherole.ofcellmediatedimmuneresponseingraftrejection.
(I0
efineautoimmunity..
Explainthe"
roleofmolecularmimicry
and
J
fLA'
haploty]
toimmunity.
(10
ritean
accounton
immuneresponse
totumors,
(I
0
.
.
escribehow
genetically
engineered
antibodies
areproduced.·rit~notes
on
productionof
subunitvaccines.
(10.
(IU-
.
.
-..
.
~
lyean
account
ofimmunofluorescene
andits
application
in
immunocytochemistry.
.(lo
hatisprecipitinreaction?Explain
any
two
precipitin.tests..
(]O
r
esentan
~CCOililt
onprinciples
~rid·
applicationof
r~di()ilnin~~l~
as~ay.-·..
(10cplainELISAtechnique
and
itsapplication.
(10
*****

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