Gold Franks Manual of Toxicologic Emergencies

Sections

Contributors
Table of Antidotes in Brief
Preface
Acknowledgments
1 Historical Principles and Perspectives
Antiquated Antidotes
2 Toxicologic Plagues and Disasters in History
PART ATHE GENERAL APPROACH TO MEDICAL TOXICOLOGY
3 Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes
4 Principles of Managing the Poisoned or Overdosed Patient
5 Electrocardiographic Principles
6 Diagnostic Imaging
7 Laboratory Principles
8 Techniques Used to Prevent Gastrointestinal Absorption
Syrup of Ipecac
Activated Charcoal
Whole-Bowel Irrigation and Other Intestinal Evacuants
9 Pharmacokinetic and Toxicokinetic Principles
10Principles and Techniques Applied to Enhance Elimination
11Use of the Intensive Care Unit
PART BTHE FUNDAMENTAL PRINCIPLES OF MEDICAL TOXICOLOGY
Section I.Biochemical and Molecular Basis
12Chemical Principles
13Biochemical and Metabolic Principles
14Neurotransmitters and Neuromodulators
15Withdrawal Principles
Section II.Pathophysiologic Basis: Organ Systems
16Thermoregulatory Principles
17Fluid, Electrolyte, and Acid–Base Principles
18Psychiatric Principles
19Neurologic Principles
20Ophthalmic Principles
21Otolaryngologic Principles
22Respiratory Principles
23Cardiovascular Principles
24Hematologic Principles
25Gastrointestinal Principles
26Hepatic Principles
27Renal Principles
28Genitourinary Principles
29Dermatologic Principles
Section III.Special Populations
30Reproductive and Perinatal Principles
31Pediatric Principles
32Geriatric Principles
33Postmortem Toxicology
Special Considerations: Organ Procurement from Poisoned Patients
PART CTHE CLINICAL BASIS OF MEDICAL TOXICOLOGY
Section I.Case Studies
A.Analgesics and Antiinflammatory Medications
34Acetaminophen
N-Acetylcysteine
35Salicylates
Sodium Bicarbonate
37Colchicine and Podophyllin
38Opioids
Opioid Antagonists
B.Foods, Dietary and Nutritional Agents
39Dieting Agents and Regimens
40Iron
Deferoxamine
41Vitamins
42Essential Oils
43Herbal Preparations
44Athletic Performance Enhancers
45Food Poisoning
46Botulism
Botulinum Antitoxin
C.Pharmaceuticals
47Anticonvulsants
L-Carnitine
48Antidiabetics and Hypoglycemics
Dextrose
Octreotide
49Thyroid and Antithyroid Medications
50Antihistamines and Decongestants
Physostigmine Salicylate
51Antimigraine Medications
52Antineoplastics
Leucovorin (Folinic Acid) and Folic Acid
53Pharmaceutical Additives
D.Antimicrobials
54Antibiotics, Antifungals, and Antivirals
55Antituberculous Medications
Pyridoxine
56Antimalarials
E.Cardiopulmonary Medications
57Anticoagulants
Vitamin K
Protamine
58Calcium Channel Blockers
59 β-Adrenergic Antagonists
Glucagon
60Other Antihypertensives
61Antidysrhythmics
62Cardioactive Steroids
Digoxin-Speciﬁc Antibody Fragments (Fab)
63Methylxanthines and Selective β2-Adrenergic Agonists
F.Anesthetics & Related Medications
64Local Anesthetics
65Inhalational Anesthetics
66Neuromuscular Blockers
Dantrolene Sodium
G.Psychotropic Medications
67Antipsychotics
68Lithium
69Monoamine Oxidase Inhibitors
70Serotonin Reuptake Inhibitors and Atypical Antidepressants
71Cyclic Antidepressants
72Sedative-Hypnotics
Flumazenil
H.Substances of Abuse
73Amphetamines
74Cocaine
75Ethanol
Thiamine Hydrochloride
76Ethanol Withdrawal
77Disulﬁram and Disulﬁramlike Reactions
78 γ-Hydroxybutyric Acid
79Inhalants
80Hallucinogens
81Cannabinoids
82Nicotine and Tobacco Preparations
83Phencyclidine and Ketamine
I.Metals
84Antimony
85Arsenic
Dimercaprol (British Anti-Lewisite or BAL)
86Bismuth
87Cadmium
88Chromium
89Cobalt
90Copper
91Lead
Succimer (2,3- Dimercaptosuccinic Acid)
92Mercury
93Nickel
94Selenium
95Silver
96Thallium
Prussian Blue
97Zinc
J.Household Products
98Antiseptics, Disinfectants, and Sterilants
99Camphor and Moth Repellents
100Caustics
101Hydroﬂuoric Acid and Fluorides
Calcium
102Hydrocarbons
103Toxic Alcohols
Fomepizole
Ethanol
K.Pesticides
104Pesticides: An Overview with a Focus on Principles and Rodenticides
105Barium
106Sodium Monoﬂuoroacetate and Fluoroacetamide
107Phosphorus
108Strychnine
109Insecticides: Organic Phosphorus Compounds and Carbamates
Pralidoxime
Atropine
110Insecticides: Organic Chlorines, Pyrethrins/ Pyrethroids, and DEET
111Herbicides
112Methyl Bromide and Other Fumigants
L.Natural Toxins and Envenomations
113Mushrooms
114Plants
115Arthropods
Antivenom (Scorpion and Spider)
116Marine Envenomations
117Snakes and Other Reptiles
Antivenom (Crotaline and Elapid)
M.Occupational and Environmental Toxins
118Industrial Poisoning: Information and Control
119Simple Asphyxiants and Pulmonary Irritants
120Carbon Monoxide
Hyperbaric Oxygen
121Cyanide and Hydrogen Sulﬁde
Sodium and Amyl Nitrite
Sodium Thiosulfate
Hydroxocobalamin
122Methemoglobin Inducers
Methylene Blue
123Smoke Inhalation
N.Disaster Preparedness
124Risk Assessment and Risk Communication
125Hazmat Incident Response
HAZMAT INCIDENT RESPONSE
126Chemical Weapons
127Biologic Weapons
128Radiation
Section II.Poison Centers and Epidemiology
129Poison Prevention and Education
130Poison Information Centers and Poison Epidemiology
131International Perspectives in Medical Toxicology
132Principles of Epidemiology and Research Design
133Adverse Drug Events and Postmarketing Surveillance
134Medications, Errors, and Patient Safety
135Risk Management and Legal Principles
Index

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