RESTRICTED*/TERHAD*
3
964/1/2/MSPAPER 2 / KERTAS 2SECTION A
Question 1
(a) 1 oxygen binds to the haem groups//Initially oxygen molecule binds slowly / harder to bind (therefore the curve of graph is less steep initially). - 12 distorts shape of molecule / allosteric//easier for next oxygen to bind / nextoxygen molecule bind faster (therefore the curve is steep in the middle). - 13 when haemoglobin is saturated with oxygen, no more oxygen is able tobind with the haemoglobin (therefore the curve is level off/ less steep atthe end). - 13 m(b) 1 as the partial pressure of carbon dioxide increases, the saturation of haemoglobin with oxygen decreases / desaturation increases - 12 curve shifts to the right (Bohr effect) - 12m(c) 1 increased CO
2
levels release hydrogen/hydrogen carbonateform//decreased pH in the plasma - 12 causes the release of the oxygen by the haemoglobin/lowers affinity foroxygen - 12m(d) 1 rate of respiration increases/ demand for oxygen increases - 12 CO
2
increases/pH drops - 13 body temperature increases - 14 affinity of haemoglobin towards oxygen is lowered /More oxygen release(from haemoglobin) to body cells. - 13mTotal 10m
any
3