Prokaryotes, Viruses, andProtistans
Did Alexander the Great Die from West Nile Virus?
Historical Review
Alexander the Great and West Nile Virus Encephalitis
John S. Marr* and Charles H. Calisher†
Table.
Medical history and physical examination of Alexander the GreatPatient characteristics
Onset of final illness May 29, 323 BC
Death June 10, 323 BC
Escalating fever associated with chills
Excessive thirst, diaphoresis
Acute abdominal pain
Single episode of back pain at onset of fever
Increased weakness leading to prostration with intermittent periods of energy
Delirium
Aphonia
Terminal flaccid paralysis
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