Axia College Material
Appendix CImmune Response and Hypersensitivity
Puncture Wound Multimedia Activity
After completing the Puncture Wound Multimedia Activity, complete the table below. List the fourevents of the inflammatory response covered in the activity in the order of occurrence. Rewritethe events in your own words, using vocabulary terms from Ch. 2 of the text.
Vascular Events in an Inflammatory Response
Events Simplified description of event Professional description of event
Germs from the nail are introduced belowthe skin.When a physical irritant enters the skingerms from the object, such as a piece ofglass are introduced below the skin.2
Surrounding cells leak fluid that affect theblood vessels.Vascular changes take place when aninjury occurs and local blood vessels ,arterioles, and capillaries dilate increasingblood flow to the injury.3
The fluid affecting the surrounding bloodvessels causes the release of other cellsinto the tissue.As the blood flow increases; moreleuckocytes reach the injury andneutrophils or polymorphs line up in thecapillary walls.4
As the wounded part of the body reactsto the germs, certain cells destroy thesegerms.Neutrophils attack the bacteria or germs;destroying them.
Give a brief description and example in your own words for each of the four types ofhypersensitivity presented in Ch. 2.
Type of Hypersensitivity Description Example
Type I: Allergic/AnaphylacticThis type of hypersensitivity iscaused by allergen binding to whatis called IgE on mast cells Thisproduces either local severeinflammation or systemic severeinflammation.This could happen byan individual beingstung by a bee. Thevenom is the cause ofthe reaction..Type II: Cytotoxic/Cytolytic These two involve IgM or IgGinteracting with foreign cells tocause their destruction.
This can happen if aperson receives ablood transfusion,such as a person whohas type A blood andis given a transfusionwith type B. Massivehemolysis occurs;agglutinanation and