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Thyroid Diseases in Pregnancy

Thyroid Diseases in Pregnancy

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Published by: api-3705046 on Oct 14, 2008
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THYROID
THYROID
DISEASES IN
DISEASES IN
PREGNANCY
PREGNANCY
10/14/08
Thyroid Diseases In Pregnancy
1
Dr. Iwo-Amah
Dr. Iwo-Amah
Department of Obstetrics and
Department of Obstetrics and
Gynaecology, UPTH
Gynaecology, UPTH
10/14/08
2
Thyroid Diseases In Pregnancy
Introduction
Introduction
\ue000Pregnancy has a significant impact on normal
Pregnancy has a significant impact on normal
maternal thyroid physiology and function, many
maternal thyroid physiology and function, many
of the physiologic change in pregnancy,
of the physiologic change in pregnancy,
especially the hypermetabolic changes mimic
especially the hypermetabolic changes mimic
thyroid disease and abnormal thyroid function.
thyroid disease and abnormal thyroid function.
\ue000Thyroid disease in pregnancy is difficult to
Thyroid disease in pregnancy is difficult to
diagnose because there is hypertrophy of the
diagnose because there is hypertrophy of the
thyroid gland due to normal gravid physiologic
thyroid gland due to normal gravid physiologic
changes.
changes.
\ue000Normal secretion from the thyroid gland contain
Normal secretion from the thyroid gland contain
approx 80% thyroxine (T4) and 20% Tri-
approx 80% thyroxine (T4) and 20% Tri-
iodothyronine (T3), T3 is the active thyroid
iodothyronine (T3), T3 is the active thyroid
hormone, most of which is derived from
hormone, most of which is derived from
peripheral conversion of thyroxine (T4)
peripheral conversion of thyroxine (T4)
\ue000Though total T4 and T3 increase, there is also an
Though total T4 and T3 increase, there is also an
increase in thyroid binding globulin (TBG),
increase in thyroid binding globulin (TBG),
albumin and re \u2013 albumin, due to enhanced
albumin and re \u2013 albumin, due to enhanced
Classification
Classification
10/14/08
3
Thyroid Diseases In Pregnancy
\ue000Thyroid diseases in pregnancy are
Thyroid diseases in pregnancy are
classified into 3 broad headings;
classified into 3 broad headings;
\ue000Hypothyroidism
Hypothyroidism
\ue000Thyroiditis
Thyroiditis
\ue000Hyperthyroidism
Hyperthyroidism

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