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Lecture 21 - Hypersensitivity

Lecture 21 - Hypersensitivity

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Published by: api-3703352 on Oct 15, 2008
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03/18/2014

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HYPERSENSITIVITY
HYPERSENSITIVITY
\u2022Foreign Ag induces localized, specific, protective
inflammation

\u2022Hypersensitivity is an undesirable, exaggerated
immune response (HMI or CMI) of detriment to the
host

\u2022Hypersensitivity reactions can be divided into
sensitizationand effectorphase s
Types of Hypersensitivity
Immediate (Types I-III)
mediated by Ab or Ag-Ab
develops within min-hrs
Delayed (Type IV)
mediated by CMI (defence against
intracellular pathogens)
develops in days

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