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Lecture 56 - 3rd Asessment - Cestodes

Lecture 56 - 3rd Asessment - Cestodes

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03/18/2014

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CESTODES
GENERAL: Adults: Intestine; Larvae: tissues of vertebrates.
Segments-
proglottids,
hermaphroditic, genital opening, flattened dorso-ventrally, scolex-suckers/hooks.
PHYSIOLOGY: Adults in lumen - anaerobic metabolism.
Glycogen from dextrose.
Nourishment from semi-digested food,
tegument with microtriches (proximal-
distal
portion for attachment).
Proteins from ntestinal mucosa,
carbohydrates
from intestinal contents.
Starvation reduces parasites.
Larvae-nourishment from host tissue.
Reproductive organs highly developed.
LIFE CYCLE: Intermediate host (exception?).
Larvae solid or vesicular.
PATHOGENICITY:Ad ul ts:Min imal ,
no definite systemic effects (toxic?),
-
D. latum.

Vit. B12 deficiency.
a. Attachment of scoleces-avenue of bacterial invasion.
b. Strobila-temporary intestinal obstruction.
c. Vague GIT and nervous symptoms.
d. Lowered vitality and anemia eg. D. latum.

Larvae: Serious disease-Cysticerci in brain (tumour?) Pressure symptoms;
shock,
dissemination.
SYMPTOMS: Due to toxic products of worm, mechanical irritation, deprive host of
food (proteins,Vitamins etc.).
RESISTANCE / IMMUNITY: Larvae provoke immunological response.
Physiochemical environment for susceptibility.
eg.
proteolytic enzymes
important
for hatching ova,
bile to activate
oncosphere.
\u201cCrowding effect\u201d.
Larvae: No striking cellular response.
Barrier between larvae and tissue not

complete,
host proteins in cyst fluid and leakage of antigen. Complement consumed-evade
immune response?

DIAGNOSIS:Scolex,
proglottids, ova. Larvae: serology, tests interpretation.
ADULT CESTODES
Species: Taenia solium,
Taenia saginata
T. SOLIUM
GEOG. DISTRIBUTION:
MORPHOLOGY:Sco lex,
Gravid proglottid, Ova (thin hyaline membrane)

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