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Bases Moleculares Hematopoyesis

Bases Moleculares Hematopoyesis

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Published by: api-3706745 on Oct 15, 2008
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03/18/2014

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Hematopoyesis
\u2022Producci\u00f3n diaria de c\u00e9lulas hem\u00e1ticas:
\u2013GR 200.000 millones
\u2013GB 70.000 millones
\u2022Sin embargo es inefeciente s\u00f3lo un 5% alcanzan el estad\u00edo final de
maduraci\u00f3n
\u2022Vida Media de las c\u00e9lulas hem\u00e1ticas:

\u2013GR 120 d\u00edas
\u2013Granulocito 6-8 horas
\u2013Plaqueta 7-10 d\u00edas

\u00cdndices
\u2022Hematocrito (Ht)
\u201347\u00b1 5 %
\u201342\u00b1 5 %
\u2022Hemoglobina (Hb)
\u201313-15,5 g/dL
\u201312,5-14 g/dL
\u2022Velocidad de Sedimentaci\u00f3n
Globular (VSG)
\u20132-8 mm/h
\u20132-10 mm/h

\u2022Hemoglobina Corpuscular Media (HCM)
HCM = Hb(g/L)/n\u00ba de eritrocitos (cel/L)
HCM = 150 g/L/5 x 101 2 cel./L =30 x 10- 12 g/cel

\u2022Concentraci\u00f3n Media de Hemoglobina
Corpuscular (CMHC)
CMHC = Hb(g/L)/Ht
CMHC = 150 g/L/0,45 = 333 g/L, 33 %.

\u2022Volumen Corpuscular Medio (VCM)
VCM = Ht/n\u00ba de eirtrocitos
VCM = 0,45 / 5 x 101 2 cel./L = 90 fL

Un eritrocito tiene un diametro aprox. 7,5\u00b5, un volumen de 90 fL y contiene 30 pg de Hb que ocupan el 33 % del volumen celular

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