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Local Anaesthetics Slides Dec25th 2006

Local Anaesthetics Slides Dec25th 2006

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Published by: api-3703352 on Oct 15, 2008
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03/18/2014

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LOCAL
ANAESTHETICS
Pharmacology & Toxicology Department
Dr. Mariam Yousif
December 25th, 2006
Objectives

2. What is the basis for the classification of local
anaesthetics (LAs) into the two classes of
esters and amides? Identify individual drug
examples from each class.

2. What is the mechanism of action of LAs?
3. Identify pharmacokinetic properties of LAs.
4. Why vasoconstrictors are used as adjuncts in

local anaesthesia.
5. What are the main adverse effects of LAs?
Local Anaesthetics (LAs)

Defined as drugs used clinically to
produce reversible loss of
sensation in a specific area of the
body

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