Adrenoreceptors
Adrenoreceptors or Adrenergic receptors are
membrane
bound
G-protein
coupled receptors which function primarily by increasing or decreasing the intracellular production of second messenger cAMP/IP3 DAG.
Classification and Location
of adrenoreceptor
There are main two types of adrenoreceptors\u03b1 &\u03b2. In this
classification there again two types of\u03b1 & three types of
\u03b2-receptors.
Subtypes of\u03b1 receptors are\u03b11 &\u03b12 while subtypes of\u03b2 receptors are\u03b21,\u03b22,\u03b23,.\u03b11 is located in vein pupil bladder sphincter, pilometor &\u03b12 in arterioles, CNS, kidney & platelets.
\u03b21 receptors are those in the myocardium and kidney, \u03b22
are those in the smooth muscles & most other sites like
Beta Blockers
Introduction
All beta adrenoceptors blocking agents are synthetic compounds and competitively inhibit the action of adrenergic agonist on beta receptors.
Beta blockers are competitive inhibitor of the
effect of catecholamine at beta adrenergic
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