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The Prevention of Alzheimers

The Prevention of Alzheimers

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Published by diney m e willemen
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Published by: diney m e willemen on Oct 20, 2011
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© 2009 ARPF. All rights reserved. Reproduction without written permission is prohibited by law.
The Prevention of 
Alzheimer’s Edges Ever
The 4 Pillars of 
 Alzheimer’s Prevention
Dharma Singh Khalsa, M.D.
President/Medical Director,
Alzheimer’s Research and
Prevention Foundation
Alzheimer’s disease slowly robs a
person of their mind, memory, andpersonality. As the dreaded illnessinches on, the patient no longerrecognizes his or her family, lovedones, or himself. According to recentreports, it is our most feared disease;even more so than cancer.When I first began my research andwriting on this subject over fifteenyears ago and created t
he Alzheimer’s
Prevention Foundation, there wereapproximately four million Americans
with Alzheimer’s. Today
, there are overfive million people in the USAdiagnosed with the disease andperhaps as many as five hundredthousand undiagnosed people living in
society with Alzheimer’s.
Beyond that, the numbers continue torise, with estimates reaching as high assixteen million Americans with thedisease in our life-time. Worldwide,these numbers are predicted to sky-rocket to around eighty million peopleby 2050.
Moreover, while Alzheimer’s is often
considered a disease of aging with 10%of the population over age 65 havingthe disease and 50% over 85 having itas well, there is a very disturbingtrend: According to Ronald Peterson of 
The Mayo Clinic, Alzheimer’s disease is
now appearing in younger people aswell, sometimes even as early as intheir twenties.How is it that someone so young can
get Alzheimer’s disease and beyond
that, why is it that some people get itand some escape? While there is noclear answer to that question, thereare a number of scientifically proven
risk factors for developing Alzheimer’s
As mentioned above, theolder you get, the risk increases.2.
The Apo E -4 genehas been shown to be associatedwith a fifty percent chance of 
developing Alzheimer’s. What
this should tell you is that havingthis gene does not necessarily
mean you’re going to get it.
Clearly, recent research reveals,
genes aren’t
everything. And, asw
soon see, there are anumber of reasonable ways toblunt the effects of genes andother risk factors.3.
A family history of 
Having a relativesuch as a grandparent, parent,aunt, uncle, or sibling with thedisease dramatically increasesyour risk.4.
There are a numberof particular environmentalfactors that modify your risk of 
© 2009 ARPF. All rights reserved. Reproduction without written permission is prohibited by law.
developing memory loss acrossyour life span. These includemodifications in your dailyactivities that you can makeright now.5.
Other risk factors.
Theseinclude head trauma,depression, heart disease, highcholesterol, thyroid disease,elevation of the amino acidhomocysteine in your blood, andlow levels of vitamin B 12 andfolic acid in your blood.But there is good news to report. Dueto recent discoveries, mainstreammedical scientists now agree with myown previous work that
disease may be able to be prevented orits onset delayed. And, veryimportantly, if we can delay the onset
of Alzheimer’s
by five years, then thenumber of cases will be halved.Additionally, if we can delay its onsetby ten years, which I believe is verypossible, a person may outlive thedevelopment of the disease and thus
Alzheimer’s disease may be eliminated
.The reason that it is possible to
prevent Alzheimer’s disease
is primarilybecause of what I call the first law of brain longevity. That law is:
yourbrain is flesh and blood just likethe rest of your body.
Because your brain is flesh and blood,there are things you can do for it tokeep it healthy and working well,regardless of your age or stage of life.Now, most excitedly, we know that youcan even grow new brain cells, aprocess called neurogenesis, build newconnections between brain cells, aprocess called neuroplasticity, andenhance your cognitive reserve or thestrength of your brain to resistdamage. Where do all these newexciting facts lead? You can enjoy alifetime of peak mental performance.So how can you build a better brainreserve, empower cognitive reserveand ev
en prevent Alzheimer’s disease?
 According to the latest researchpresented at the Second InternationalPrevention of Dementia Conferencehosted by the Chicago-based
Alzheimer’s Association in Washington
D.C., the way to develop a better,stronger brain is to make life-stylechoices similar to those of The 4 Pillars
of Alzheimer’s Prevention.
Here they are:1.
Diet and Memory SpecificNutrient Supplementation2.
Stress Management3.
Physical, Mental and Mind/BodyExercise4.
Pharmaceutical Medication andHormone Replacement Therapy.
As discussed at the conference, it’s
 exceedingly clear that what you put inyour mouth over time may influencethe development of many diseasesincluding heart disease, arthritis,
cancer, and Alzheimer’s disease.
According to nutritional research, theenemies of brain longevity are a diethigh in saturated and trans-fats as wellas eating foods that are too high insugar.In countries where the intake of fat is
high, the incidence of Alzheimer’s is
elevated as well. Moreover, new
© 2009 ARPF. All rights reserved. Reproduction without written permission is prohibited by law.
research by medical scientists hasclearly indica
ted that Alzheimer’s may
be a form of insulin resistance. In other
words, Alzheimer’s may be a type of 
diabetes in the brain.For that reason, the up-to-the-minuterecommendations are to eat a dietlimited to 20 per-cent fat rich inOmega-3 from sources such as salmonand tuna. Protein should be from leansources, and you need to make sureyou get your six to nine servings of fresh, preferably organic, fruit andvegetables each and every day.As that is still quite difficult for mostAmericans, a multiple vitamin andmineral tablet is recommended.Although there has been somecontroversy as of late regardingsupplementation with anti-oxidantvitamins such as Vitamin C, andVitamin E, the consensus is that theyare beneficial to long-term brainhealth.Other supplement research receivingpositive reviews include ginkgo,Phosphatidylserine (PS), the omega 3fatty acid DHA, turmeric, and greentea. Resveratrol, pomegranate, andblueberries are also being recognizedfor their healing properties.The newest and most exciting researchwork from the bastions of academicmedicine, however, was concerning thethree concepts I mentioned above:neuroplasticity, neurogenesis, andcognitive reserve.The keys to generating new brain cells(neurogenesis) and forging newconnections (neuroplasticity) inanimals as well as humans, appears tobe in creating
what’s known
. Research inmice by D
r. Carl Cotman’s laboratory
at the University of California in Irvine,reveals that when the little animals aregiven nice cages with treadmills andmice toys and other mice for companyas opposed to simply having the mouseput in a cage with a bowl of water andfood, they do better on memory testsand h
ave less Alzheimer’s pathology in
their brains when examined atautopsy.Dr. Rusty Cage in San Diego has alsoshown that exercising mice actuallygrows new brain cells.Numerous studies in humans supportthe benefits of exercise for your heartand cardiovascular system. It helpsprevent osteoporosis and boosts yourimmune system. Studies have alsoshown that people who exercise lowertheir risk of memory loss.Moreover, new work by investigatorScott Small, M.D., Columbia University,has conclusively shown that physicalexercise creates new brain cells inhumans. In his work, Scott has beenable to explain specifically whathappens in the brain following exercise.Exercise, they found, targets a part of the brain in the hippocampus ormemory center of the brain called thedentate gyrus, which is the areaassociated with memory loss.Dr. Small is now looking to describethe exact type of exercise that may be

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