Cortastat, Dalalone, Decadron Phosphate, Decadron Phosphate
Ophthalmic, Decadron Phosphate Turbinaire, Decaject, Dexasone, Dexone,
Hexadrol Phosphate, Solurex
Short-term management of various inflammatory and allergic disorders, such as
rheumatoid arthritis, collagen diseases (SLE), dermatologic diseases (pemphigus),
status asthmaticus, and autoimmune disorders
Contraindicated with infections, especially tuberculosis, fungal infections,
amebiasis, vaccinia and varicella, and antibiotic-resistant infections, allergy to any
component of the preparation used.
Use cautiously with renal or hepatic disease; hypothyroidism, ulcerative colitis
with impending perforation; diverticulitis; active or latent peptic ulcer;
inflammatory bowel disease; CHF, hypertension, thromboembolic disorders;
osteoporosis; seizure disorders; diabetes mellitus; lactation.
Tablets\u20140.25, 0.5, 0.75, 1, 1.5, 2, 4, 6 mg; elixir\u20140.5 mg/5 mL; oral solution\u20140.5 mg/5
mL; injection\u20148 mg/mL, 16 mg/mL, 4 mg/mL, 10 mg/mL, 20 mg/mL, 24 mg/mL;
aerosol\u201484 mcg/actuation; ophthalmic solution\u20140.1%; ophthalmic suspension\u20140.1%;
ophthalmic ointment\u20140.05%; topical ointment\u20140.05%; topical cream\u20140.05%, 0.1%;
topical aerosol\u20140.01%, 0.04%
Individualize dosage based on severity of condition and response. Give daily dose before
9 AM to minimize adrenal suppression. If long-term therapy is needed, alternate-day
therapy with a short-acting steroid should be considered. After long-term therapy,
withdraw drug slowly to avoid adrenal insufficiency. For maintenance therapy, reduce
initial dose in small increments at intervals until the lowest clinically satisfactory dose is
Individualize dosage based on severity of condition and response, rather than by strict
adherence to formulas that correct adult doses for age or body weight. Carefully observe
growth and development in infants and children on long-term therapy.
Metabolism: Hepatic; T1/2: 110\u2013210 min
Distribution: Crosses placenta; enters breast milk
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