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Biochem 11

Biochem 11

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Published by hamza jassar

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Published by: hamza jassar on Oct 17, 2008
Copyright:Attribution Non-commercial

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07/19/2013

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U N ~
 
OF
JORDAN
Faculty
OF
Medicine
I
I
LECTURE
NO:
i
1
,¢'---I
DATE: \
1.
I"
I
'LOa
&
 
BY
THE
NAME
OF
ALLAH
~ a r b Q h y d r a t c s
Mttabolis"li.Some metabolic factors
&
objective:
I-How we could utilize glucose to
get
energy.2-Ruw we could make glucose from Doncarbohydratesubstances.
3-00
Wei-Fed state glucose
stored
in the form
of
glycogen.
4 ~ H o w
 
we can degrade glycogen to get glucose.S·Wc must know bow to make gluconic acid (an
important
compound
for
dr-ug
metabolism).
6-We
can prepare
one type
of
sugar
from
other
type
(intercoDversion)
that's
because
there
is
no
essential
sugar.
We
arc
going
to
talk
on
these
pathways which
is
vcry
important
for the production
ofNADPH
(electron
carrier
forreductive biosynthesis. involve
in
reactive oxygen
species).
Glucose
is
the
primary
source
of
energy for the Nervoussystem
&
for
RBC.
In
aerobic conditions, glucose converts intoPyruvate but
under
anaerobic conditions it
COD\'erts
into Lactate.
 
-In
our
bodies, we got about
40
to
50%
of
energy from
carbohydrate
35%
of
energy from fat15%
of
energy from protein-60%
of
carbohydrates
are
preferable
to
be complex starch(bread,
p o t a t o ~
...etc), the remaining
carbohydrate are
come fromsucrose (table sugar), Disaccharide. monosaccharide,
Bnd
fromanimals glycogen as
weD
as lactose (from milk).Some compounds
and
the Jinks between:Amylopectin 1-6
,
Glycogen
1-6
Fructose
a
1-2
Lactose
p
1-4Cellulose
p
1-4
(we caD't digest this I)
~ i ~ e s t i o n :
 
I.Digestion
of
carbohydrate
start at
the mouth where
we
have Alpha-Amylase enzyme which acts
00
thee starch and glycogen.
The
end product
of
this process
is
(maltose, isomaltose (1-6 linkage)and dextrin (short branch oligosaccharide).
I

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