CONTENTS
A*STAR
Research
www.astar-research.com
A*STAR
Research
is a publication o the Agency or Science, Technologyand Research (A*STAR)—Singapore’s lead government agency orostering world-class scientic research.
A*STAR
Research
is published twice a year, presenting researchhighlights and eature articles. All articles are rst published online on the
A*STAR
Research
website and available ree to all readers. Registeronline to receive the table o contents by email as each biweekly onlineissue is published.© 2011 A*STAR. This publication may be reproduced in its original ormor personal use only. Modication or commercial use without priorpermission rom the copyright holder is prohibited.
Editorial
Agency or Science, Technology and Research1 Fusionopolis Way, #20-10 Connexis North TowerSingapore 138632, SingaporeEditor-in-Chie Charles ZukoskiEditorial Board Paola CastagnoliKwong Dim-LeeLim Khiang WeeEdison LiuPernille RorthManaging Editor Kostas RepanasAdministrative Assistant Fion CheongISSN 2010-0531
Research Highlights
3
CELL BIOLOGY & IMMUNOLOGY
Cooperating partners | A matter o balance | The cause o joint pain | Getting into shape | Preventing signal overload |Reprogramming with synthetic proteins | Many ways to reach out | Communication breakdown | Learning throughinteraction | Stem cell signaling | Many ways to ght inection | Dierentiation in the balance | The origin o esophageal cancer
17
CHEMISTRY & MATERIALS
Amino acids made easy | Finding riends with a golden tip | Split personality | Go with the fow | Let it snow | Stress and strain |Going green with steam | Bubble chemistry | Getting nickel back | Taking the direct approach | Optimum solution |Composite catalysts | Solar express | Copying geckos’ toes | Reversal o ortune
33
GENETICS & DISEASE
Inside the decision-making process | The key to transormation | Gut instincts | Size matters | Tightening the belt on tumorgrowth | An old drug revisited | Hand and bone patterning gene | How malaria gets into the brain | More than skin deep |Markers or lymphoma | A x or ragile skin
45
PHYSICAL & LIFE SCIENCE TECHNOLOGIES
Sweet and simple | Flu tracking | A handy kit | Simulating amyloid ormation | Loading up a cure | In tune with the brain |Chewing the at | Dierent places, dierent rules | A test or toxicity | The right gear or the right job | Spotting abdominallesions | Authenticating ancient artiacts | Raman probes or cancer diagnostics | An ear or the cutting edge | Under the‘scope | Bacterial killers | Demystiying natural hierarchy
63
ENGINEERING & NANOTECHNOLOGY
Miniature magnetic switches | Hitting all the right notes | Phase o | Pillars o light | Double twist | Keeping the heat on |Plasmonics on the grid | Fast and light | A better business model | Through the crystal spheres | Perect graphene dots | A closerlook | Bright prospects | One and only | Better solar cells around the corner | Wireless liberation | The vibration that smoothes
82
The key to data reedom
83
An impermeable wrap or utureelectronics
84
New ways to harvest light
86
Saeguarding air travel
88
Streamlined asset managementtakes fight
89
Local environs explained, andmarketed, in a click
90
Tweaking targets or antibiotics
92
Game-changing microfuidics
Features and Innovations