The outer living boundary of the cell is called as the cell membraneor ‘Plasma membrane’. The term cell membrane was coined by C.J.Nageli and C. Crammer in 1855. Apart from the cell membrane, eachand every organelle in the cell is also covered by membranes. The cellmembrane not only limits the cell cytosol, but it has a variety of functionslike membrane transport, signal transduction and neuro transmission.
To study the chemical composition of the cell membrane, thepreferred source is RBC, because they lack cell organelles and thus nocontamination of other cellular organelle membranes. The membranes of the RBCs devoid of cytosol are called as ‘ghosts’.Four major constituents are present in the cell membrane. Theyare (i) lipids (28 – 79%) (ii) proteins (20 – 70%). (iii) oligosaccharides(only 1 – 5%) and (iv) water (20%).
Depending upon the tissue from which the cell membrane isisolated, the composition also differs. Nearly 80% of the myelin sheath ismade up of lipids, while in liver, it constitutes only 28%.
For circulation to students in Medical and Biomedical disciplinesPlan: Section 1. Biochemistry for learners: pages 2- 234Section 2. Illustrated Medical Biochemistry: pages 235-391Section 3: Book material for Clinical Chemistry: pages 392-1346Section 4: Practice exercises and MCQ: 1347-1659_________________________________________________________TEXT eBOOKS INCLUDED_________________________________________________________