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Integrative Approaches to Molecular Biology

Integrative Approaches to Molecular Biology

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Published by: api-3844880 on Oct 18, 2008
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03/18/2014

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edited by Julio Collado-Vides, Boris Magasanik, and Temple F. Smith
huangzhiman 200212.26
www.dnathink.org
Integrative Approaches to
Molecular Biology
CONTENTS
Preface
vii
1Evolution as Engineering
Richard C. Lewontin
1
IComputational Biology
11
2Analysis of Bacteriophage T4 Based on the Completed DNA Sequence
Elizabeth Kutter
13
3The Identification of Protein Functional Patterns
Temple F. Smith, Richard Lathrop, and Fred E. Cohen
29
4Comparative Genomics: A New Integrative Biology
Robert J. Robbins
63
5On Genomes and Cosmologies
Antoine Danchin
91

II
Regulation, Metabolism, and Differentiation: Experimental and Theoretical
Integration

113
6A Kinetic Formalism for Integrative Molecular Biology: Manifestation in
Biochemical Systems Theory and Use in Elucidating Design Principles for Gene
Circuits
Michael A. Savageau
115
7Genome Analysis and Global Regulation in Escherichia coli
Frederick C. Neidhardt
147
8Feedback Loops: The Wheels of Regulatory Networks
Ren\u00a8\u00a6 Thomas
167
\u00a1\u00a1
9
Integrative Representations of the Regulation of Gene Expression
Julio Collado-Vides
179
10
Eukaryotic Transcription
Thomas Oehler and Leonard Guarente
205
11
Analysis of Complex Metabolic Pathways
Michael L. Mavrovouniotis
211
12
Where Do Biochemical Pathways Lead?
Jack Cohen and Sean H. Rice
239
13
Gene Circuits and Their Uses
John Reinitz and David H. Sharp
253
14
Fallback Positions and Fossils in Gene Regulation
Boris Magasanik
273
15
The Language of the Genes
Robert C. Berwick
281
Glossary
297
References
303
Contributors
331
Index
335

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