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Leucemias Agudas e Cronicas

Leucemias Agudas e Cronicas

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Published by: api-3719960 on Oct 19, 2008
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03/18/2014

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LEUCEMIAS AGUDAS
LEUCEMIAS AGUDAS

Prolifera\u00e7\u00e3o monoclonal de c\u00e9lula maligna progenitora, de origem hematopoi\u00e9tica, que \u00e9 incapaz de se diferenciar, mas extremamente capaz de se dividir e multiplicar.

1. CONCEITO
2. EPIDEMIOLOGIA

3 % das neoplasias - USA
LMA : + comum
LLA : na inf\u00e2ncia (< 12 anos) - mais frequente

3. ETIOLOGIA

\u2022a) Radia\u00e7\u00f5es Ionizantes
\u2022b) Altera\u00e7\u00f5es Cromossomiais
\u2022c) Agentes Qu\u00edmicos (benzeno, agentes

alquilantes, fenilbutazona)
\u2022d) V\u00edrusEBV \u2013 Epstein-Barr
HTLV-1 \u2013 Human T Lynphotropic Virus
LEUCEMIAS AGUDAS
LEUCEMIAS AGUDAS
Os blastos neopl\u00e1sicos s\u00e3o lan\u00e7ados na corrente sangu\u00ednea,
levando ao quadro de leucocitose. Podem infiltrar diversos \u00f3rg\u00e3os.

Aten\u00e7\u00e3o: a aus\u00eancia de blastos na corrente sangu\u00ednea n\u00e3o
exclui o diagn\u00f3stico de leucemia aguda, alguns pacientes
podem ser diagnosticados numa fase em que a neoplasia
est\u00e1 restrita a medula \u00f3ssea \u2013 leucemia aleuc\u00eamica.

Anemia
Expans\u00e3o Bl\u00e1stica -
Neutropenia
Trombocitopenia
4. FISIOPATOLOGIA

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