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Emulsion

Emulsion

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Published by: Syifaturrahmah Nurfalah on Nov 21, 2011
Copyright:Attribution Non-commercial

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02/02/2013

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EMULSIONS
 
Emulsions:
¡
Definition:
Itisthermodynamicallyunstablesystemconsistingofatleasttwoimmiscibleliquidphasesoneofwhichisdispersedasglobules(thedispersedphase)intheotherliquidphase(thecontinuousphase)stabilizedbypresenceofemulsifyingagent.
To stabilize thesedroplets, emulsifyingagent should be added
-Particle diameter of dispersed phase (Internal phase) ranged from0.1 to 10 um.
 
Pharmaceutical applications ofemulsions:
¡
1.Theycanmaskthebittertasteandodorofdrugs,e.g.castoroil,cod-liveroiletc.
¡
2.Theycanbeusedtoprolongthereleaseofthedrugtherebyprovidingsustainedreleaseaction.
¡
3.Essentialnutrientslikecarbohydrates,fatsandvitaminscanallbeemulsifiedandcanbeadministeredtobedriddenpatientsassterileintravenousemulsions.
¡
4.Emulsionsprovideprotectiontodrugswhicharesusceptibletooxidationorhydrolysis.
¡
5.Intravenousemulsionsofcontrastmediahavebeendevelopedtoassistindiagnosis.
¡
6.Emulsionsareusedwidelytoformulateexternallyusedproductslikelotions,creams,linimentsetc.

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