Welcome to Scribd. Sign in or start your free trial to enjoy unlimited e-books, audiobooks & documents.Find out more
Standard view
Full view
of .
Look up keyword
Like this
0 of .
Results for:
No results containing your search query
P. 1
Fpgee test practice

Fpgee test practice



|Views: 4,533|Likes:
Published by api-3830277

More info:

Published by: api-3830277 on Oct 19, 2008
Copyright:Attribution Non-commercial


Read on Scribd mobile: iPhone, iPad and Android.
download as DOC, PDF, TXT or read online from Scribd
See more
See less





Question 1
The right answer was
The removal of drug is independent of drug concentration.
Question 2
The right answer was
Excretion rate.
Question 3
The answer is Extraction ratio
Question 4
The right answer was
 All are correct.
Question 5
The right answer was
2.4 mg.
Question 6
The right answer was
1.25 mg.
Question 7
The right answer was
30 L/hr/70 Kg.
Question 8
The right answer was
a & b.
Question 9
The right answer id CYP51
Question 10
The right answer was
Question 11
The right answer was
 All of the above.
Question 12
The right answer was
Both carry out oxidative deaminations.
Question 13
The right answer was
Glucuronide conjugation.
Question 14
The right answer was
Question 15
The right answer was
In a zero order elimination process, which of thefollowing is true?
The removal of drug is independent of drug concentration
Cl = Elimination rate/Cp
t1/2 = .7VD/Cl
All are true
For highly polar drugs (e.g. mannitol) what primarilydetermines elimination rate?
Excretion rate
Metabolism rate
Absorption rate
Distribution rate
All of the above
Bioavailability is related to which of the followingparameters, according to the equation F = 1 - E
Extraction Ratio
Enterohepatic Recycling
For the majority of drugs, which of the followingequations correctly defines clearance?
Cl = Elimination rate/Cp
Cl = QxE
Cl = .7VD/t1/2
All are correct
How much of a 10 mg dose of morphine reaches thesystemic circulation given F = .24?
0.24 mg
2.4 mg
4.1 mg
Given that the VD = 230 L/70Kg and Cl = 60 L/hr/70Kg for morphine, approximately how much of a 10 mgIV dose remains after 8 hr, given to a normal 70 Kgpatient?
5 mg
2.5 mg
1.25 mg
625 mg
Given F = .24, what is the overall hepatic clearance of morphineif the above patient has portal hypertension such that theirhepatic blood flow is reduced by ½? Assume the clearancevalue given in the previous question is entirely hepaticclearance.

Activity (50)

You've already reviewed this. Edit your review.
1 hundred reads
1 thousand reads
Sreelatha Yarava added this note
very useful.
Abdelnour Kello liked this
Dickson Enebuse liked this
Peter Samy liked this
Felix Ferreiro liked this

You're Reading a Free Preview

/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->