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Molecular Oncogenes and Cancer Gene Therapy

Molecular Oncogenes and Cancer Gene Therapy

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Published by: api-3858544 on Oct 19, 2008
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03/18/2014

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By:Hussain albaharna
Oncogenes and proto-oncogenes

\u2022Scientists discovered in the late 1970s that a specific
gene type plays a major role in the carcinogenesisof the
cell, the so-called proto-oncogenes

\u2022Oncogenes are mutated forms of proto-oncogenes
whose functions are to encourage and promote the,
normal growth and division of cells. When proto-
oncogenes mutate to become carcinogenic oncogenes,
the result is excessive cell multiplication
\u2022Generally, proto-oncogenes code for cellular proteins
that relay signals, to a cell's nucleus, stimulating growth
(continue)
\u2022Proto-oncogenes activation to oncogenes
may result in:

\u2022overproduction of growth factors.
\u2022flooding of the cell with replication signals .
\u2022uncontrolled stimulation in the.

intermediary pathways and/or
\u2022unrestrained cell growth driven by
elevated levels of transcription factors.
Oncogenes and proto-oncogenes

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