Classification and external resources
Micrograph of metastatic Ewing sarcoma (right of image) in normal lung (leftof image). PAS stain.
is amalignant round-cell tumour.It is a rare disease in whichcancer cells are found in thebone or in soft tissue. Themost common areas in whichit occurs are the pelvis, thefemur, the humerus, the ribsand clavicle.Because a common geneticlocus is responsible for a largepercentage of Ewing sarcomaand primitive neuroectodermaltumors, these are sometimesgrouped together in a categoryknown as the Ewing family of tumors.
The diseases are,however, considered to bedifferent: peripheral primitiveneuroectodermal tumours aregenerally not associated withbones, while Ewing sarcomasare most commonly related tobone.Ewing sarcoma occurs mostfrequently in male teenagers,with a male/female ratio of 1.6:1.
Although usually classified as a bone tumour, Ewing sarcoma can have characteristics of bothmesodermal and ectodermal origin, making it difficult to classify.
1 Eponym2 Causes3 Clinical findings4 Imaging findings5 Clinical differential diagnosis6 Diagnosis7 Epidemiology8 Treatment8.1 Fertility preservationPage 1 of 4Ewing's sarcoma - Wikipedia, the free encyclopedia7/7/2011http://en.wikipedia.org/wiki/Ewing's_sarcoma