Principles of Human Anatomy and Physiology, 11e4
DEVELOPMENT OF MUSCLE
•With few exceptions, muscles develop from
•Skeletal muscles of the head and extremities develop from
; the remainder of the skeletal musclesdevelop from
mesoderm of somites
Somite—one of a paired, block-like masses of mesodermarranged segmentally alongside the neural tube of theembryo, forming the vertebral column and segmentalmusculature.
Principles of Human Anatomy and Physiology, 11e5
Developmental Anatomy of the Muscular System
•Develops from mesoderm•Somite formation –blocks of mesoderm give riseto vertebrae and skeletalmuscles of the back•Muscles of head & limbs developfrom general mesoderm
Principles of Human Anatomy and Physiology, 11e6
Fusion of Myoblasts into Muscle Fibers
•Mature muscle cells developed from 100 myoblasts that fuse together inthe fetus. (multinucleated)•Mature muscle cells are not known to divide.•Muscle growth is a result of cellular enlargement (hypertrophy) & not celldivision (hyperplasia)•Satellite cells retain the ability to regenerate new cells.