Table 4 - Immunizing agents and schedules for health-care workers
Immunizing agentPrimary schedule and boostersHepatitis A vaccine
Two doses of vaccine either 6-12 monthsapart.Hepatitis B (recombinant ) vaccine
Two doses IM 4 weeks apart; third dose 5months after second; booster doses notnecessary.Influenza vaccine (inactivated whole-virusand split-virus vaccines)
Annual vaccination with current vaccine.Administered IM.Measles live-virus vaccine
One dose SC; second dose at least 1 monthlater.Mumps live-virus vaccine
One dose SC; no booster.Pneumococcal polysaccharide vaccine (23valent)
One dose, 0.5 ml, IM or SC; revaccinationrecommended for those at highest risk >5years after the first dose.Rubella live-virus vaccine
One dose SC; no booster.Tetanus and diphtheria toxoids vaccine
Two IM doses 4 weeks apart; third dose 6-12months after second dose; booster every 10years.Varicella-zoster vaccine
Two 0.5 ml doses SC 4-8 weeks apart if > 13years of age.
From: Immunization of Health-care workers. MMWR. December 26, 1997. 46/No.RR-18.
Not routinely indicated for HCWs in the United States. Persons who work with HAV-infected primates or with HAV in a research laboratory setting should be vaccinated. Thesafety of the HAV vaccine in pregnant women has not been determined.
On the basis of limited data, no adverse effects to developing fetuses is apparent.Pregnancy should not be considered a contraindication to vaccination of women. Thevaccine produces neither therapeutic nor adverse effects on HBV infected persons.Prevaccination serologic screening is not indicated for persons being vaccinated for occupational risk.
HCWs who have contact with patients at high risk for influenza or its complication; HCWswho work in chronic care facilities; HCWs who work with high-risk medical conditions or who are aged >65 years. No evidence of risk to mother or fetus when the vaccine isadministered to a pregnant woman with an underlying high risk condition. The vaccine isrecommended during the 2
trimesters of pregnancy because of increased for hospitalization.