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04-04-06geneticsofimmunity

04-04-06geneticsofimmunity

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Published by: Sarah Beth Whicker Breck on Jan 04, 2012
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01/04/2012

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Human Genetics:
concepts and applications6th editionRicki Lewis
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Chapter 17
Genetics of Immunity
 
17-2
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Immunity
Immune system protectsorganisms from foreigninvaders.Transplanted tissue isrecognized as foreign unlessonly shared cell surfacemolecules are present.
This father donated part of his liver for daughter withcystic fibrosis.
 
17-3
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Foreign versus self 
To protect the body from harmful organisms, the immunesystem identifies foreign molecules as ´nonselfµ and destroysthose cells.
 ±
Bacteria
 ±
 Yeast
 ±
Viruses
 ±
Tumor cells
 ±
Transplanted cells
Molecules recognized by the immune system are calledantigens. Antigens are usually protein fragments or carbohydrates.
Immune response to one·s own body is calledautoimmunity.

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