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Pediatric Antimicrobial Dosing

Pediatric Antimicrobial Dosing

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Published by: damondouglas on Nov 10, 2008
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12/08/2012

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University of Maryland Medical Center 
Pediatric Antimicrobial Intravenous Dosing Guidelines( > 2 kg and > 7 days old)DRUG IV DOSE FREQUENCY MAX/DOSEAmikacin*
7.5 - 10 mg/kg/doseper renal functionN/A
Amphotericin B
0.3 1 mg/kg/24hq 24 hN/A
Ampicillin
100 400 mg /kg/24hq 6 h3 gm
Ampicillin/Sulbactam
100 400 mg /kg/24hq 6 h3 gm
(Unasyn)
(as ampicillin component)
Azithromycin
10 mg/kg/24h Day 1q 24 h 500 mg5 mg/kg/ 24h Day 2 to 5
Cefazolin
50 100 mg /kg/24hq 8 h1 gm
Cefepime*
50 mg/kg/ doseq 8 h2 gm
Cefotetan
20 40 mg/kg/doseq 12 h2 gm
Cefoxitin
80 160 mg/kg/24hq 6 h2 gm
Ceftriaxone
50 100 mg/kg/24hq 24 h 2 gmq 12 h (for meningitis)
Ciprofloxacin*
15 20 mg/kg/24hq 12 h400 mg
Clindamycin
25 40 mg/kg/24hq 6 h 8 h900 mg
Doxycycline
2 4 mg/kg/24hq 12 h 100 mg
Erythromycin
20 50 mg/kg/24hq 6 h1 gm
Fluconazole
3 12 mg/kg/24hq 24 h800 mg
Gentamicin
2.5 mg/kg/doseper renal functionN/A
Metronidazole
30 mg/kg/24hq 6 h 1 gm
Nafcillin
150 200 mg/kg/24hq 6 h2 gm
 
Penicillin G
100,000400,000 u/kg/24hq 4 h4 mln units
Piperacillin/Tazobactam
200 400 mg/kg/24hq 6 h4 gm
(Zosyn)
(as piperacillin component)
Ticarcillin/Clavulanate
200 - 300 mg/kg/24hq 6 h 3 gm
(Timentin)
(as ticarcillin component)
TMP/SMX
6 20 mg/kg/24hq 12 h 6 hN/A
(Bactrim, Septra)
(as TMP component)
Vancomycin*
10 15 mg/kg/24hper renal functionN/A
*Requires ID approval.Women’s and Children’s Pharmacy Central Pharmacy
Hours:Telephone Number: 8- 5644Monday to Friday 7 am to 10 pmSaturday & Sunday 7 am to 8 pmFax Number: 8- 8474Telephone Number 8 – 8950Fax Number 8 - 7163Beeper Numbers: 0847: S6U, S6D, FTN, L&D, MBU8476: S5U, S5D, S5A, S5B, P4GClinical Specialist Beeper: 2411
Updated 8/2000

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