Drug

Dosage

Action

Indication

Contraindication

Adverse effect

Nursing responsibilities

Omeprazole (losec)

40mg TIV, OD

Classification: Gastrointestinal Agent; Proton Pump Inhibitor

Gastric acid-pump inhibitor: Suppresses gastric acid secretion by specific inhibition of the hydrogenpotassium ATPase enzyme system at the secretory surface of the gastric parietal cells; blocks the final step of acid production.

Short-term treatment of active duodenal ulcer; First-line therapy in treatment of heartburn or symptoms of gastroesophageal reflux disease (GERD); Short-term treatment of active benign gastric ulcer; GERD, severe erosive esophagitis, poorly responsive symptomatic GERD; Long-term therapy: Treatment of pathologic hypersecretory conditions (Zollinger-Ellison

Contraindicated with hypersensitivity to omeprazole or its components; Use cautiously with pregnancy, lactation.

CNS: 1. Assessment Headache , History: dizziness, y Hypersensitivity to asthenia, vertigo, omeprazole or any insomnia, apathy, of anxiety, its components; paresthesias, pregnancy, lactation dream abnormalities Physical:
y

Dermatologic: Rash, inflammation, urticaria, pruritus, alopecia, dry skin GI: Diarrhea, abdominal pain, nausea, vomiting, constipation, dry mouth, tongue atrophy

Skin lesions; reflexes, affect; urinary output, abdominal exam; respiratory auscultation Interventions

2. Administer before meals. Caution patient to swallow capsules whole,not to open, chew, or crush them.

syndrome, multiple adenomas, systemic mastocytosis); Eradication of H. pylori with amoxicillin or metronidazole and clarithromycin; Prilosec OTC: Treatment of frequent heartburn (2 or more days per wk); Unlabeled use: Posterior laryngitis; enhance efficacy of pancreatin for the treatment of steatorrhea in cystic fibrosis

Respiratory: U RI symptoms,cough, epistaxis Other: Cancer in preclinical studies, back pain, fever