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CDMRP Gulf War Illness Research Program, May 2010

CDMRP Gulf War Illness Research Program, May 2010

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Published by Anthony Hardie
"Gulf War Illness Research Program": Congressionally Directed Medical Research Program (CDMRP), U.S. Army Medical Research and Materiel Command, U.S. Department of Defense. Funded by Congressional directed funding in FY10 Defense Appropriations Act. Date of Publication: May 2010
"Gulf War Illness Research Program": Congressionally Directed Medical Research Program (CDMRP), U.S. Army Medical Research and Materiel Command, U.S. Department of Defense. Funded by Congressional directed funding in FY10 Defense Appropriations Act. Date of Publication: May 2010

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Published by: Anthony Hardie on Jan 30, 2012
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Gulf War Illness Research Program
 
2
 The Congressionally Directed Medical ResearchPrograms (CDMRP) was born in 1992 from apowerful grassroots effort led by the breast cancer advocacy com-munity that resulted in a congressional appropriation of funds forbreast cancer research. This initiated a unique partnership amongthe public, Congress, and the military. Since then, the CDMRP hasgrown to encompass multiple targeted programs and has received
almost $5.9 billion in appropriations from its inception in scal year
1993 (FY93) through FY10. Through FY09, approximately 9,700awards have been made across 19 different programs. Funds forthe CDMRP are added by Congress to the Department of Defense(DOD) budget annually to provide support for targeted research
programs in breast, prostate, and ovarian cancers; neurobromato
-sis; autism; and other areas with military health interests includingpsychological health, traumatic brain injury, and Gulf War Illness(GWI). Under the auspices of the U.S. Army Medical Researchand Materiel Command (USAMRMC), the CDMRP manages theseprograms from receipt of funds, competitive selection of proposals,through individual project performance, to closeout.
HISTORY
Congessional  Appropriaion ReceipoFunds ision Seting ReleaseoProgram  Announcemen Proposal ReceipPee Reie Pogammaic Reie  Approal o Commanding GeneralNegotiaions  Aard Execution (1– 5eas)
 
Congi Appropriaione Nearl 6,800scientiss,clinicians, consumeadocates,and ohepofessionals hae boughheiexpeiseoscientiic pee eie.PoMoehan 300old-r enoned scientist s, clinicians,policmakers, and consumeadocaes haeserv edonhe CDMRPs Inegaion Panels.oenMore than6,400 scienistsand clinicians hae eceied more han 9,000 aardsrom heCDMRP. Moe than120scientist s, clinicians, and proessionals managehe CDMRP.
 The CDMRP program management cycleincludes a two-tier review process for proposalevaluation recommended by the NationalAcademy of Science’s Institute of Medicine.
 The rst tier of evaluation is an externalscientic peer review of proposals againstestablished criteria for determining scientic
merit. The second tier is a programmaticreview conducted by a CDMRP-convenedIntegration Panel (IP) composed of program-
specic researchers, clinicians, and consum
-ers who evaluate proposals on innovation,potential impact, programmatic priorities,
and mechanism-specic criteria. The Commanding Generalof USAMRMC issues the nal approval for funding prior to award
negotiations and execution.
Congressionally
 
Directed MedicalResearch Programs
 
Gulf War Illness Research Program
3
HISTORY
DOD GWI Research Investment
BasicResearch11Pr o jectsExposur es Research4Pro jectsSymptoms Research7PojectsIdentifyingBiomarker s6Pro jectsTreatmentStudies7Pr ojects
GWIRP Funded Portfolioby Research Topic, FY06-FY09
(n=35 Projects*)
Gulf War IllnessResearch Program
DOD-funded GWI research began in 1994 with the establish-ment of a Gulf War Veterans’ Illnesses Research Program(GWVIRP) to study the health effects of service membersdeployed in the 1990–1991 Persian Gulf War. From FY94 toFY05, the GWVIRP was managed by the USAMRMC MilitaryOperational Medicine Research Program (MOMRP). Researchpertaining to GWI also was funded intermittently through theCDMRP’s Peer Reviewed Medical Research Program (PRMRP), which supports military health-related research. The MOMRPshared management responsibility for the GWVIRP with theCDMRP in FY06 with separate $5 million appropriations.Although the GWVIRP did not receive funding in FY07, a $10million appropriation renewed the program in FY08, renamedthe Gulf War Illness Research Program (GWIRP), to be managedfully by the CDMRP. The GWIRP has continued in FY09 andFY10 with an $8 million appropriation each year. The programis directed to support peer reviewed research of treatments for
the complex of symptoms that comprise GWI, identication
of objective markers (biomarkers) for the disease, and under-standing the pathobiology underlying GWI.
VISION
Improve the health and livesof veterans who have Gulf WarIllness.
mISSION
Fund innovative Gulf WarIllness research to identifyeffective treatments, improve
denition and diagnosis,
and better understandpathobiology and symptoms.
PRMRP (CDMRP)GW VIRP(MOMRP) ALSTD*(CDMRP)
05152030351025
       F       Y       9       4       F       Y       9       5       F       Y       9       6       F       Y       9       7       F       Y       9       8       F       Y       9       9       F       Y       0       0       F       Y       0       1       F       Y       0       2       F       Y       0       3       F       Y       0       4       F       Y       0       5       F       Y       0       6       F       Y       0       7       F       Y       0       8       F       Y       0       9       F       Y       1       0
    M    i    l    l    i   o   n   s    (    $    )
GWIRP(CDMRP)
* 7 Po jects tinto 2different ResearchTopics
*Amyotr opicLatealSclerosisTheapeutic Development

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