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bio 103 tut Translation

bio 103 tut Translation

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Published by bab3lis
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Used for concept maps

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Published by: bab3lis on Dec 06, 2007
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06/16/2009

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The process of translating the mRNA data (nucleotide chain) into Proteins (Amino-acid chains).1.The mRNA is binding to the Ribosome’s small unit (mRNA binding site).2.A tRNA with bound methionine (amino-acid that binds to a tRNA, that has the UAC anti-codon, whichis complementary to the start codon AUG ) is sliding over the mRNA, from it’s “cap”, until it finds the1
st
AUG sequence, and stops there.3.The Ribosome’s large subunit is attaching to the tRNA, locating it in its P-site.4.A tRNA (with bound amino-acid) will enter the A-site, in condition that it has anti-codon that iscomplementary to the next codon on the mRNA .5.Enzymes will create a peptide bond between the A-site amino-acid and the P-site peptide chain (or onlymethionine) .6.The large subunit slides over the mRNA to a distance of 3 nucleotides, so the A-site will now be parallelto a new codon, the tRNA from A-site will move to P-site, and the tRNA from P-site will move to E-site(and exit from the Ribosome).

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